The two-volume set LNCS 9516 and 9517 constitutes the thoroughly refereed proceedings of the 22nd International Conference on Multimedia Modeling, MMM 2016, held in Miami, FL, USA, in January 2016.The 32 revised full papers and 52 poster papers were carefully reviewed and selected from 117 submissions. In addition 20 papers were accepted for five special sessions out of 38 submissions as well as 7 demonstrations (from 11 submissions) and 9 video showcase papers. The papers are organized in topical sections on video content analysis, social media analysis, object recognition and system, multimedia retrieval and ranking, multimedia representation, machine learning in multimedia, and interaction and mobile. The special sessions are: good practices in multimedia modeling; semantics discovery from multimedia big data; perception, aesthetics, and emotion in multimedia quality modeling; multimodal learning and computing for human activity understanding; and perspectives on multimedia analytics.