Sets the stage for the design and application of new protein
cages
Featuring contributions from a team of international experts in
the coordination chemistry of biological systems, this book enables
readers to understand and take advantage of the fascinating
internal molecular environment of protein cages. With the aid of
modern organic and polymer techniques, the authors explain step by
step how to design and construct a variety of protein cages.
Moreover, the authors describe current applications of protein
cages, setting the foundation for the development of new
applications in biology, nanotechnology, synthetic chemistry, and
other disciplines.
Based on a thorough review of the literature as well as the
authors’ own laboratory experience, Coordination Chemistry in
Protein Cages
* Sets forth the principles of coordination reactions in natural
protein cages
* Details the fundamental design of coordination sites of small
artificial metalloproteins as the basis for protein cage
design
* Describes the supramolecular design and assembly of protein
cages for or by metal coordination
* Examines the latest applications of protein cages in biology
and nanotechnology
* Describes the principles of coordination chemistry that govern
self-assembly of synthetic cage-like molecules
Chapters are filled with detailed figures to help readers
understand the complex structure, design, and application of
protein cages. Extensive references at the end of each chapter
serve as a gateway to important original research studies and
reviews in the field.
With its detailed review of basic principles, design, and
applications, Coordination Chemistry in Protein Cages is
recommended for investigators working in biological inorganic
chemistry, biological organic chemistry, and nanoscience.
关于作者
TAKAFUMI UENO is Professor in the School and Graduate
School of Bioscience and Biotechnology at Tokyo Institute of
Technology. His current research interests involve the molecular
design of artificial metalloproteins and exploitation of meso-scale
materials with the coordination chemistry of protein assemblies. He
was awarded the Young Investigator Award of the Japan Society of
Coordination Chemistry in 2007 and the Young Scientists’ Prize of
the Commendation for Science and Technology by the Minister of
Education, Culture, Sports, Science and Technology, Japan, in
2008.
YOSHIHITO WATANABE is Professor in the Department of
Chemistry at Nagoya University. Since 2009, he has been appointed a
Vice President of Research and International Affairs. His current
research interests include the design of hydrogen
peroxide-dependent monooxygenase and construction of metalloenzymes
with synthetic complexes at their catalytic centers. He is a
recipient of the Chemical Society of Japan Award for Creative Work
in 1999, and the Japan Society of Coordination Chemistry in 2011.
He sits on two editorial boards and an international advisory
board.
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