Biomedical Photonic Technologies
A state-of-the-art examination of biomedical photonic research, technologies, and applications
In Biomedical Photonic Technologies, a team of distinguished researchers delivers a methodical inquiry and evaluation of the latest developments in the field of biomedical photonics, with a focus on novel technologies, including optical microscopy, optical coherence tomography, fluorescence imaging-guided surgery, photodynamic therapy dosimetry, and optical theranostic technologies.
Each discussion of individual technologies includes examples of their contemporary application in areas like cancer therapy and drug delivery. Readers will discover the major research advancements in biomedical photonics from the last 20 years, ascertaining the basic principles of formation, development, and derivation of biomedical photonics phenomena at a variety of scales. Readers will also find:
- A thorough introduction to advanced wide-field fluorescent microscopy for biomedicine
- Comprehensive explorations of fluorescence resonance energy transfer and optical coherence tomography for structural and functional imaging
- Practical exploration of coherent Raman scattering microscopy and biomedical applications, as well as fluorescence image-guided surgery
- Complete analyses of enhanced photodynamic therapy, optogenetics, and optical theranostics employing gold nanoparticles
Perfect for biophysicists and applied physicists, Biomedical Photonic Technologies will also benefit bioengineers and biotechnologists in academia and in industry.
Table of Content
OPTICAL MICROSCOPY
Optical Section
Super-Resolution Microscope
FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET)
Process of Fluorescence Emission
Process and Properties of FRET
The Donors-Acceptors Couple (D-A Couple) Theory of FRET
Types of FRET Process
Common Fluorescent Groups of FRET
Optical Properties of D-A Couple in FRET System
Qualitative FRET Detection
Quantitative FRET Detection
Common Instruments of FRET Signal Detection and Analysis
Applications of FRET in Biomedicine
OPTICAL COHERENCE TOMOGRAPHY (OCT)
Imaging Mechanism of OCT
OCT Functional Imaging
Applications for OCT
COHERENT RAMAN SCATTERING MICROSCOPY
Introduction
Coherent Anti-Stokes Raman Scattering Microscopy
Stimulated Raman Scattering Microscopy
Biomedical and Biological Applications of CRS Microscopy
Prospects and Challenges
FLUORESCENCE IMAGING GUIDED SURGERY
Introduction
Fluorescence Probes for Imaging Guided Surgeries
Imaging Systems
Typical Fluorescence Imaging Guide Surgeries
Limitations and Challenges
PHOTODYNAMIC THERAPY DOSIMETRY
Introduction
Implicit Dosimetry
Explicit Dosimetry
Biological Response
Singlet Oxygen Luminescence Dosimetry
Challenges and Perspectives
OPTICAL TISSUE PHANTOMS FOR IMAGING AND SPECTROSCOPY
Introduction
Absorption, Scatter and Fluorescence Phantom Composition
Typical Tissue Phantoms
Methods for Measuring Optical Properties of the Phantoms
Applications of Tissue Phantoms
Future Prospects
OPTICAL THERANOSTIC TECHNOLOGIES BASED ON PRECIOUS METAL NANOPARTICLES
Optical Properties of Gold Nanoparticles (GNPs)
GNPs-Mediated Optical Diagnostic Technology
GNPs-Mediated Phototherapy for Cancer
GNPs-Mediated Precision Treatment
About the author
Zhenxi Zhang, Ph D, is a Professor at the School of Life Science and Technology of Xi’an Jiaotong University, China. His research focus is on biomedical photonics imaging and spectral analysis techniques.
Shudong Jiang, Ph D, is a Professor at the Thayer School of Engineering of Dartmouth College, USA. Her research focus is on optical spectroscopy and imaging systems for biomedical applications.
Buhong Li, Ph D, is a Professor of Biomedical Photonics at the School of Science of Hainan University, China. His research is focused on optical technologies and instrumentation for monitoring photodynamic therapy dosimetry.