Catalog > Sciences > Medicals > Clinical Subjects > Dieter Köberle & Oliver Gautschi: KRAS-Mutationsstatus und kolorektales Karzinom (PDF)

Dieter Köberle & Oliver Gautschi
KRAS-Mutationsstatus und kolorektales Karzinom [PDF ebook]

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Cover of Dieter Köberle & Oliver Gautschi: KRAS-Mutationsstatus und kolorektales Karzinom (PDF)

Kirsten rat sarcoma (KRAS)-Mutationen zählen zu den häufigsten onkogenen Mutationen in Tumoren. Mit dem besseren Verständnis der Schlüsselfunktion von KRAS wird beim kolorektalen Karzinom erstmals eine an molekularen Merkmalen ausgerichtete individualisierte Therapie ermöglicht, bei der frühzeitig beurteilt werden kann, welche Patienten von einer hochspezialisierten Behandlung einen besseren Nutzen ziehen können.
Dieses Lehrbuch vermittelt die aktuellen Kenntnisse zu KRAS-Mutationen und deren Bedeutung für die Therapie des Kolorektalkarzinoms. Es erläutert die biochemischen Grundlagen und diskutiert den Stellenwert von Biomarkern in der Diagnostik sowie die Konsequenzen für die Therapie mit Anti-EGFR-Antikörpern.
Das Buch wurde von namhaften Spezialisten aus dem deutschsprachigen Raum verfasst und richtet sich an alle Personen, die an der medikamentösen Therapie des kolorektalen Karzinoms interessiert sind.

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Language German ● Format PDF ● Pages 95 ● ISBN 9783837452259 ● File size 2.6 MB ● Publisher UNI-MED Verlag AG ● City Bremen ● Country DE ● Published 2010 ● Edition 1 ● Downloadable 24 months ● Currency EUR ● ID 7944700 ● Copy protection Social DRM

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