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Dieter Köberle & Oliver Gautschi
KRAS-Mutationsstatus und kolorektales Karzinom [PDF ebook]

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Copertina di Dieter Köberle & Oliver Gautschi: KRAS-Mutationsstatus und kolorektales Karzinom (PDF)

Kirsten rat sarcoma (KRAS)-Mutationen zählen zu den häufigsten onkogenen Mutationen in Tumoren. Mit dem besseren Verständnis der Schlüsselfunktion von KRAS wird beim kolorektalen Karzinom erstmals eine an molekularen Merkmalen ausgerichtete individualisierte Therapie ermöglicht, bei der frühzeitig beurteilt werden kann, welche Patienten von einer hochspezialisierten Behandlung einen besseren Nutzen ziehen können.
Dieses Lehrbuch vermittelt die aktuellen Kenntnisse zu KRAS-Mutationen und deren Bedeutung für die Therapie des Kolorektalkarzinoms. Es erläutert die biochemischen Grundlagen und diskutiert den Stellenwert von Biomarkern in der Diagnostik sowie die Konsequenzen für die Therapie mit Anti-EGFR-Antikörpern.
Das Buch wurde von namhaften Spezialisten aus dem deutschsprachigen Raum verfasst und richtet sich an alle Personen, die an der medikamentösen Therapie des kolorektalen Karzinoms interessiert sind.

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Lingua Tedesco ● Formato PDF ● Pagine 95 ● ISBN 9783837452259 ● Dimensione 2.6 MB ● Casa editrice UNI-MED Verlag AG ● Città Bremen ● Paese DE ● Pubblicato 2010 ● Edizione 1 ● Scaricabile 24 mesi ● Moneta EUR ● ID 7944700 ● Protezione dalla copia DRM sociale

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