This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.
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Formato EPUB ● Páginas 676 ● ISBN 9781135545246 ● Editor Rajni Hatti-Kaul & Bo Mattiasson ● Editorial CRC Press ● Publicado 2003 ● Descargable 3 veces ● Divisa EUR ● ID 8002350 ● Protección de copia Adobe DRM
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