Board on Health Care Services & Board on Health Sciences Policy 
Evolution of Translational Omics [PDF ebook] 
Lessons Learned and the Path Forward

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Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient’s likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

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Langue Anglais ● Format PDF ● Pages 354 ● ISBN 9780309224192 ● Éditeur Christine M. Micheel & Gilbert S. Omenn ● Maison d’édition National Academies Press ● Publié 2012 ● Téléchargeable 3 fois ● Devise EUR ● ID 7143789 ● Protection contre la copie Adobe DRM
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