Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient’s likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
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भाषा अंग्रेज़ी ● स्वरूप PDF ● पेज 354 ● ISBN 9780309224192 ● संपादक Christine M. Micheel & Gilbert S. Omenn ● प्रकाशक National Academies Press ● प्रकाशित 2012 ● डाउनलोड करने योग्य 3 बार ● मुद्रा EUR ● आईडी 7143789 ● कॉपी सुरक्षा Adobe DRM
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