Induced pluripotent stem (i PS) cell technology has paved new ways for disease modeling and drug discovery. Disease modeling with the differentiated neuronal cells from patient-specific i PS cells partially recapitulated the phenotypes of spinal muscular atrophy, familial dysautonomia and Rett syndrome. In this book, the authors present current research in the study of induced stem cells, including the cryopreservation of pluipotent stem cells; tissue engineering approaches using bioactive ceramics towards bone regeneration; induced pluripotent stem cell-derived hepatocytes as an alternative to human adult hepatocytes; i PS technology for studying neurodegenerative diseases and i PS from cord blood cells.