Alfredo Ulloa-Aguirre & Ya-Xiong Tao 
Targeting Trafficking in Drug Development [PDF ebook] 

समर्थन

Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.

€223.63
भुगतान की विधि

विषयसूची

1. Intracellular trafficking of gonadotropin receptors in health and disease.- 2. Investigating internalization and intracellular trafficking of GPCRs.- 3. Pharmacological chaperones as potential therapeutic strategies for misfolded mutant vasopressin receptors.- 4. Targeting of disordered proteins by small molecules in neurodegenerative diseases.- 5. Pharmacoperones for misfolded gonadotropin receptors.- 6. Pharmacological chaperones: Beyond conformational disorders.- 7. Natural (and unnatural) small molecules as pharmacological chaperones and inhibitors in cancer.- 8. Heritable skeletal disorders arising from defects in processing and transport of Type I procollagen from the ER: perspectives on possible therapeutic approaches.- 9. Conserved oligomeric Golgi and neuronal vesicular trafficking.- 10. SLC6 transporter folding diseases and pharmacochaperoning.- 11. The molecular physiopathogenesis of islet amyloidosis.- 12. Folding defects leading to primary hyperoxaluria.- 13. Potentialpharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.

यह ईबुक खरीदें और 1 और मुफ़्त पाएं!
भाषा अंग्रेज़ी ● स्वरूप PDF ● पेज 425 ● ISBN 9783319741642 ● फाइल का आकार 11.0 MB ● संपादक Alfredo Ulloa-Aguirre & Ya-Xiong Tao ● प्रकाशक Springer International Publishing ● शहर Cham ● देश CH ● प्रकाशित 2018 ● डाउनलोड करने योग्य 24 महीने ● मुद्रा EUR ● आईडी 6200964 ● कॉपी सुरक्षा के बिना

एक ही लेखक से अधिक ईबुक / संपादक

1,318 इस श्रेणी में ईबुक