Alfredo Ulloa-Aguirre & Ya-Xiong Tao 
Targeting Trafficking in Drug Development [PDF ebook] 

Stöd

Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.

€223.63
Betalningsmetoder

Innehållsförteckning

1. Intracellular trafficking of gonadotropin receptors in health and disease.- 2. Investigating internalization and intracellular trafficking of GPCRs.- 3. Pharmacological chaperones as potential therapeutic strategies for misfolded mutant vasopressin receptors.- 4. Targeting of disordered proteins by small molecules in neurodegenerative diseases.- 5. Pharmacoperones for misfolded gonadotropin receptors.- 6. Pharmacological chaperones: Beyond conformational disorders.- 7. Natural (and unnatural) small molecules as pharmacological chaperones and inhibitors in cancer.- 8. Heritable skeletal disorders arising from defects in processing and transport of Type I procollagen from the ER: perspectives on possible therapeutic approaches.- 9. Conserved oligomeric Golgi and neuronal vesicular trafficking.- 10. SLC6 transporter folding diseases and pharmacochaperoning.- 11. The molecular physiopathogenesis of islet amyloidosis.- 12. Folding defects leading to primary hyperoxaluria.- 13. Potentialpharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.

Köp den här e-boken och få 1 till GRATIS!
Språk Engelska ● Formatera PDF ● Sidor 425 ● ISBN 9783319741642 ● Filstorlek 11.0 MB ● Redaktör Alfredo Ulloa-Aguirre & Ya-Xiong Tao ● Utgivare Springer International Publishing ● Stad Cham ● Land CH ● Publicerad 2018 ● Nedladdningsbara 24 månader ● Valuta EUR ● ID 6200964 ● Kopieringsskydd utan

Fler e-böcker från samma författare (r) / Redaktör

1 318 E-böcker i denna kategori