In somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure. Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed `sperm chromatin condensation’. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa.
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स्वरूप PDF ● पेज 137 ● ISBN 9781616684952 ● संपादक Ali Reza Talebi ● प्रकाशक Nova Science Publishers ● प्रकाशित 2016 ● डाउनलोड करने योग्य 3 बार ● मुद्रा EUR ● आईडी 7219443 ● कॉपी सुरक्षा Adobe DRM
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