Statins work by reducing cholesterol synthesis by inhibiting the enzyme HMG-Co A reductase. The decrease in cholesterol levels is associated with increased expression of receptors of hepatocytes, with a greater extraction of plasma LDL-C and a lower diffusion of it into the tissues. In this book, the authors present current research in the study of the pharmacology, clinical implications and adverse effects of statins. Topics include the pleiotropic effects of statins beyond cholesterol lowering; anti-inflammatory activity of statins in asthma and COPD; statins as anticancer agents; statin use in patients with carotid disease; and the Alzheimer’s disease risk-lowering effect of lipophilic statins.
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स्वरूप PDF ● पेज 210 ● ISBN 9781620813935 ● संपादक Benedetta La Grua & Alessandro Molinelli ● प्रकाशक Nova Science Publishers ● प्रकाशित 2007 ● डाउनलोड करने योग्य 3 बार ● मुद्रा EUR ● आईडी 7220955 ● कॉपी सुरक्षा Adobe DRM
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