Statins work by reducing cholesterol synthesis by inhibiting the enzyme HMG-Co A reductase. The decrease in cholesterol levels is associated with increased expression of receptors of hepatocytes, with a greater extraction of plasma LDL-C and a lower diffusion of it into the tissues. In this book, the authors present current research in the study of the pharmacology, clinical implications and adverse effects of statins. Topics include the pleiotropic effects of statins beyond cholesterol lowering; anti-inflammatory activity of statins in asthma and COPD; statins as anticancer agents; statin use in patients with carotid disease; and the Alzheimer’s disease risk-lowering effect of lipophilic statins.
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Biçim PDF ● Sayfalar 210 ● ISBN 9781620813935 ● Editör Benedetta La Grua & Alessandro Molinelli ● Yayımcı Nova Science Publishers ● Yayınlanan 2007 ● İndirilebilir 3 kez ● Döviz EUR ● Kimlik 7220955 ● Kopya koruma Adobe DRM
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