The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
75 द्वारा ईबुक Jamie A. Goode
Gregory R. Bock & Jamie A. Goode: Molecular Mechanisms Influencing Aggressive Behaviours
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding …
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Gregory R. Bock & Jamie A. Goode: Signalling Networks in Cell Shape and Motility
This book features contributions from experts in cell biology,
genetics, neurobiology, immunology and structural biology.
The unifying element is that they all study processes of cell shape
change …
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Gregory R. Bock & Jamie A. Goode: Genetics of Autoimmunity
This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene …
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Derek J. Chadwick & Jamie A. Goode: The hERG Cardiac Potassium Channel
This book draws together contributions from basic, pharmaceutical
and clinical sciences aimed at a better understanding of the
structure and function of h ERG and the molecular basis for compound …
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Gregory R. Bock & Jamie A. Goode: Understanding Nicotine and Tobacco Addiction
Cigarette smoking is estimated to lead to 4.9 million premature
deaths per year worldwide. This is predicted to rise to 10 million
by 2020. In western countries it kills half of all smokers who …
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Gregory R. Bock & Jamie A. Goode: Heart Failure
Heart failure is the main cause of death and disability in the
industrialized world. There is a major need for novel therapeutics
for prevention and reversal of cardiac pathology associated with …
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Derek J. Chadwick & Jamie A. Goode: Epithelial Anion Transport in Health and Disease
Cl- absorption and HCO3- secretion are intimately associated
processes vital to epithelial function, itself a key physiological
activity. Until recently the transporters responsible remained …
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Derek J. Chadwick & Jamie A. Goode: Mast Cells and Basophils
The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to …
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Gregory R. Bock & Jamie A. Goode: Empathy and Fairness
Empathy is the process that allows us to share the feelings and
emotions of others, in the absence of any direct emotional
stimulation to the self. Humans can feel empathy for other people
in a …
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Derek J. Chadwick & Jamie A. Goode: Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely
important cell-cell signalling molecule for a wide variety of
cells across evolutionarily diverse organisms. The extracellular …
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Derek J. Chadwick & Matthew Diamond: Percept, Decision, Action
Seemingly simple behaviours turn out, on reflection, to be
discouragingly complex. For many years, cognitive operations such
as sensation, perception, comparing percepts to stored models …
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Derek J. Chadwick & Jamie A. Goode: Signalling Pathways in Acute Oxygen Sensing
Oxygen sensing is a key physiological function of many tissues, but
the identity of the sensor, the signalling pathways linking the
sensor to the effector, and the endpoint effector mechanisms are …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Innate Immunity to Pulmonary Infection
Part of the prestigious Novartis Foundation series, this volume
uniquely addresses the use of innate immunity to treat or prevent
infectious diseases of the lung.
Innate Immunity to Pulmonary …
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Gregory R. Bock & Jamie A. Goode: New Treatment Strategies for Dengue and Other Flaviviral Diseases
Dengue virus is a member of the Flaviviridae family, which includes
viruses associated with human diseases such as yellow fever,
Japanese encephalitis and hepatitis C. Dengue fever is
transmitted …
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Gregory R. Bock & Jamie A. Goode: Decoding the Genomic Control of Immune Reactions
This book explores existing and potential strategies for using the
genome sequences of human, mouse, other vertebrates and human
pathogens to solve key problems in the treatment of immunological …
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Derek J. Chadwick & Jamie A. Goode: Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) comprises a group of idiopathic
diseases of the intestine characterized by chronic inflammation of
the bowel with periods of exacerbation and remission. Although …
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Gregory R. Bock & Jamie A. Goode: Immunoinformatics
The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element …
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Derek J. Chadwick & Jamie A. Goode: Molecular Clocks and Light Signalling
The ability at the molecular level to keep track of time is a
property shared by organisms ranging from the simplest unicells to
humans. The primary feature of these biological clocks is their …
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Gregory R. Bock & Jamie A. Goode: Stem Cells
Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated …
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Gregory R. Bock & Gerry Chader: Retinal Dystrophies
Retinal dystrophies are the major causes of incurable blindness in
the Western world. Our insight into their aetiology has
improved remarkably over the past decade and a number of key genes
have …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Nuclear Organization in Development and Disease
This book draws together contributions from cell and developmental
biologists, structural biologists, geneticists and clinical
scientists aimed at a better understanding of the cellular and …
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Gregory R. Bock & Jamie A. Goode: Tinkering
Much recent research in evolutionary developmental biology has
focused on the origin of new body plans. However, most evolutionary
change at the population and species level consists of tinkering: …
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Derek J. Chadwick & Jamie A. Goode: Vascular Development
The formation of blood vessels is an essential aspect of
embryogenesis in vertebrates. It is a central feature of
numerous post-embryonic processes, including tissue and organ
growth and …
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Gregory R. Bock & Jamie A. Goode: Dietary Supplements and Health
Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and ‘bioactive components’ commonly found in foods. They are marketed …
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Derek J. Chadwick & Jamie A. Goode: Acetaldehyde-Related Pathology
Part of the prestigious Novartis Foundation, this is the first book
to review the pathology associated with acetaldehyde, a known toxic
agent found in cigarette smoke and other pollutants and …
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€163.99
Joan Marsh & Jamie A. Goode: The GTPase Superfamily
Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the …
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€121.99
Derek J. Chadwick & Joan Marsh: The Molecular Basis of Smell and Taste Transduction
Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the …
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Joan Marsh & Jamie A. Goode: Germline Development
Connects classical cellular descriptive studies with more recent work on the molecular and genetic aspects regarding germline development. Prominent scientists discuss research on a range of …
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€121.99
Gregory R. Bock & Jamie A. Goode: Higher-Order Processing in the Visual System
Foremost neurophysiologists and psychophysicists provide pertinent information on the nature of representation at the earliest stages as this will constrain the disposition of all subsequent …
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Joan Marsh & Jamie A. Goode: Antimicrobial Peptides
Describes the structure and function of important peptides from several different organisms. An exciting development is the use of these peptides or their analogues in the treatment and prevention of …
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€121.99
Joan Marsh & Jamie A. Goode: Cell Adhesion and Human Disease
Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic …
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€121.99
Gregory R. Bock & Jamie A. Goode: Non-Reproductive Actions of Sex Steroids
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids’ effects on the nervous and immune systems. Provides an …
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Derek J. Chadwick & Jamie A. Goode: The Molecular Biology and Pathology of Elastic Tissues
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics …
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Gregory R. Bock & Jamie A. Goode: Genetics of Criminal and Antisocial Behaviour
This book offers a fresh perspective on the controversial topic of criminal and antisocial behavior. It synthesizes findings from behavioral and population genetics, evolutionary biology and …
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Gregory R. Bock & Jamie A. Goode: Growth Factors as Drugs for Neurological and Sensory Disorders
Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye …
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Derek J. Chadwick & Jamie A. Goode: P2 Purinoceptors
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, …
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€121.99
Gregory R. Bock & Jamie A. Goode: The Nature and Origin of Amyloid Fibrils
Amyloid fibrils are associated with a range of pathological disorders including Alzheimer’s Disease, Down’s syndrome, diabetes, cardiomyopathies, and transmissible spongiform encephalopathies. This …
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€121.99
Gregory R. Bock & Jamie A. Goode: Evolution of Hydrothermal Ecosystems on Earth (and Mars?)
This book explores the possibility that life exists on Mars. It provides an interdisciplinary overview of the early evolution of life in hydrothermal ecosystems on Earth, focusing on the problem of …
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€121.99
Gregory R. Bock & Jamie A. Goode: The Molecular Basis of Cellular Defence Mechanisms
The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the ‘property’ of immunologists, the …
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€121.99
Derek J. Chadwick & Jamie A. Goode: Antibiotic Resistance
Antibiotic Resistance: Origins, Evolution, Selection and Spread
Chairman: Stuart B. Levy, 1997
Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also …
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€121.99
Gregory R. Bock & Jamie A. Goode: Precision Agriculture
This book investigates new agricultural systems such as organic and green manuring, as well as integrated pest management practices, and looks at how they can improve farm productivity against the …
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Gregory R. Bock & Jamie A. Goode: Plasminogen-Related Growth Factors
A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic …
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Gregory R. Bock & Jamie A. Goode: The Limits of Reductionism in Biology
A comprehensive volume examining the fundamental questions raised by reductionists’ theory about levels of explanation necessary to understand biological systems. The book evaluates the enormously …
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€108.99
Gregory R. Bock & Jamie A. Goode: Immunological Tolerance
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and …
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€108.99
Derek J. Chadwick & Jamie A. Goode: Alcohol and Cardiovascular Disease
Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together much new and exciting work in this area, it reviews …
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€108.99
Gregory R. Bock & Jamie A. Goode: Sensory Guidance of Movement
Sensory Guidance of Movement
Chairman: Mitchell Glickstein, 1998
In the past few years there has been an increasing recognition of the multiplicity of sensory and motor areas of the cerebral …
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€108.99
Gregory R. Bock & Jamie A. Goode: Environmental Statistics
Environmental statistics is a rapidly growing discipline that is
important not only as a division of professional and academic
statistics, but also in the accumulation of data on
environmental …
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€108.99
Derek J. Chadwick & Jamie A. Goode: Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence
Chair: John A. Pickett, 1999
This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and …
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€163.99
Ikuo Takeuchi & Gregory R. Bock: Rhodopsins and Phototransduction
Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the …
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€108.99
Jamie A. Goode & Derek J. Chadwick: Rice Biotechnology
Rice is the most important food crop for half the world’s population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively …
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€161.99
Gregory R. Bock & Jamie A. Goode: Defining Optimal Immunotherapies for Type 1 Diabetes
* This book is a comprehensive and up-to-date account of where we
stand in immunological strategies for preventing or treating type 1
diabetes (T1D).
* Brings together contributions from the …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Mitochondrial Biology
With the recent renaissance in mitochondrial biology and increasing
recognition of their role in many diseases, this book provides a
timely summary of the current state-of-the-art in mitochondrial …
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Derek J. Chadwick & Jamie A. Goode: Growth Factors and Psychiatric Disorders
The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes …
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€163.99
Jamie A. Goode & Derek J. Chadwick: The Biology of Extracellular Molecular Chaperones
The heat shock, or cell stress, response was first identified in
the polytene chromosomes of Drosophila. This was later
related to the appearance of novel proteins within stressed cells,
and the …
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Gregory R. Bock & Jamie A. Goode: Novel and Re-emerging Respiratory Viral Diseases
The past decade has seen mounting global concern regarding viral
outbreaks such as SARS, avian influenza and West Nile virus. In
2004 and 2005, reports of bird-to-human, and possible …
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Derek J. Chadwick & Jamie A. Goode: Role of the Sarcoplasmic Reticulum in Smooth Muscle
Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as …
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Derek J. Chadwick & Jamie A. Goode: Cancer and Inflammation
Chronic inflammation predisposes to some forms of cancer and the
host response to malignant disease shows several parallels with
inflammation and wound healing. The cells involved in inflammation …
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€163.99
Gregory R. Bock & Jamie A. Goode: ‘In Silico’ Simulation of Biological Processes
Over recent decades vast amounts of biological data have been
accumulated. However, it is becoming increasingly difficult to
apply traditional theoretical methods to the formulation of
coherent …
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Derek J. Chadwick & Jamie A. Goode: Mucus Hypersecretion in Respiratory Disease
A number of chronic respiratory diseases including chronic
bronchitis, asthma, cystic fibrosis and bronchiectasis are
characterized by mucus hypersecretion. Following damage to the
airway …
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Gregory R. Bock & Jamie A. Goode: Anaphylaxis
Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding …
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Derek J. Chadwick & Jamie A. Goode: Mammalian TRP Channels as Molecular Targets
This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It covers the structure, function and regulation of …
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€161.99
Gregory R. Bock & Jamie A. Goode: Reversible Protein Acetylation
A comprehensive review of recent work on chromatin and non-histone proteins, this book arises from the interactions of a multidisciplinary group of scientists involved in the study of acetylation. …
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Gregory R. Bock & Jamie A. Goode: Tissue Engineering of Cartilage and Bone
Tissue engineering takes advantages of the combined use of cultured
living cells and three-dimensional scaffolds to reconstruct adult
tissues that are absent or malfunctioning. This book brings …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Osteoarthritic Joint Pain
Osteoarthritis is a chronic degenerative disease associated with
joint pain and loss of joint function. It has an estimated
incidence of 4 out of every 100 people and significantly reduces
the …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Development of the Cardiac Conduction System
The pacemaking and conduction system (PCS) is vital for generating
and synchronizing the heart beat. Dysfunction of this system
can be a direct cause of cardiac conduction disturbance,
arrhythmias …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Pathological Pain
This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages …
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€161.99
Gregory R. Bock & Jamie A. Goode: Autism
This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a …
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€163.99
Gregory R. Bock & Jamie A. Goode: Biology of IGF-1
An invaluable book containing a series of interdisciplinary
discussions between clinical and basic scientists. Biology
of IGF-1: Its interaction with insulin and health and malignant
states …
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€149.99
Derek J. Chadwick & Jamie A. Goode: Mechanisms and Biological Significance of Pulsatile Hormone Secretion
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Neuronal and Cognitive Effects of Oestrogens
Although normally thought of as a sex hormone, recent research has
highlighted the numerous and significant effects that oestrogen has
on the CNS, extending far beyond its important reproductive …
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€161.99
Derek J. Chadwick & Jamie A. Goode: Neural Transplantation in Neurodegenerative Disease
The field of neural transplantation is at a crucial stage in its development, with results of important clinical trials on transplantation in patients with Parkinson’s disease expected soon and …
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€161.99
Gregory R. Bock & Jamie A. Goode: The Nature of Intelligence
Evolutionary psychology ans behaviour genetics are two successful and important fields in the study of human behaviour, but practitioners in these two fields have different conceptions of the nature …
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€171.99
Gregory R. Bock & Jamie A. Goode: Generation and Effector Functions of Regulatory Lymphocytes
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed ‘suppressor cells’. Many recent reports have documented their existence, …
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€163.99
Gregory R. Bock & Jamie A. Goode: Fatty Acid and Lipotoxicity in Obesity and Diabetes
The potential lipotoxic effect of accumulation of fatty acids in
non-adipose tissues is thought to be a major component in the
development of insulin resistance. Chronic exposure to high …
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€163.99
Gregory R. Bock & Jamie A. Goode: Cortical Development
To understand the brain and its devastating diseases, we need to
reveal the mechanisms that produce it and the ways in which it can
constantly change throughout a lifetime. This book features a …
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€161.99
