The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
76 Электронные книги Jamie A. Goode
Gregory R. Bock & Jamie A. Goode: Molecular Mechanisms Influencing Aggressive Behaviours
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding huma …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Signalling Networks in Cell Shape and Motility
This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change an …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Genetics of Autoimmunity
This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: The hERG Cardiac Potassium Channel
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of h ERG and the molecular basis for compound bin …
PDF
английский
DRM
€149.99
Gregory R. Bock & Jamie A. Goode: Understanding Nicotine and Tobacco Addiction
Cigarette smoking is estimated to lead to 4.9 million premature deaths per year worldwide. This is predicted to rise to 10 million by 2020. In western countries it kills half of all smokers who fail …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: Heart Failure
Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with hear …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Epithelial Anion Transport in Health and Disease
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Mast Cells and Basophils
The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to stu …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Empathy and Fairness
Empathy is the process that allows us to share the feelings and emotions of others, in the absence of any direct emotional stimulation to the self. Humans can feel empathy for other people in a wide …
PDF
английский
DRM
€163.99
Derek J. Chadwick & Jamie A. Goode: Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely important cell-cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Matthew Diamond: Percept, Decision, Action
Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception, comparing percepts to stored models (short-term …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Signalling Pathways in Acute Oxygen Sensing
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are al …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Innate Immunity to Pulmonary Infection
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infecti …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: New Treatment Strategies for Dengue and Other Flaviviral Diseases
Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Decoding the Genomic Control of Immune Reactions
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological dise …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Immunoinformatics
The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Molecular Clocks and Light Signalling
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their abilit …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Stem Cells
Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated dis …
PDF
английский
DRM
€161.99
Gregory R. Bock & Gerry Chader: Retinal Dystrophies
Retinal dystrophies are the major causes of incurable blindness in the Western world. Our insight into their aetiology has improved remarkably over the past decade and a number of key genes have been …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Jamie A. Goode: Nuclear Organization in Development and Disease
This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Tinkering
Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: sm …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Vascular Development
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: Dietary Supplements and Health
Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and ‘bioactive components’ commonly found in foods. They are marketed a …
PDF
английский
DRM
€163.99
Derek J. Chadwick & Jamie A. Goode: Acetaldehyde-Related Pathology
Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived …
PDF
английский
DRM
€163.99
Joan Marsh & Jamie A. Goode: The GTPase Superfamily
Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the …
PDF
английский
DRM
€121.99
Derek J. Chadwick & Joan Marsh: The Molecular Basis of Smell and Taste Transduction
Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the la …
PDF
английский
DRM
€121.99
Joan Marsh & Jamie A. Goode: Germline Development
Connects classical cellular descriptive studies with more recent work on the molecular and genetic aspects regarding germline development. Prominent scientists discuss research on a range of organism …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Higher-Order Processing in the Visual System
Foremost neurophysiologists and psychophysicists provide pertinent information on the nature of representation at the earliest stages as this will constrain the disposition of all subsequent processi …
PDF
английский
DRM
€121.99
Joan Marsh & Jamie A. Goode: Antimicrobial Peptides
Describes the structure and function of important peptides from several different organisms. An exciting development is the use of these peptides or their analogues in the treatment and prevention of …
PDF
английский
DRM
€121.99
Joan Marsh & Jamie A. Goode: Cell Adhesion and Human Disease
Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approach …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Non-Reproductive Actions of Sex Steroids
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids’ effects on the nervous and immune systems. Provides an i …
PDF
английский
€121.99
Derek J. Chadwick & Jamie A. Goode: The Molecular Biology and Pathology of Elastic Tissues
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics inclu …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Genetics of Criminal and Antisocial Behaviour
This book offers a fresh perspective on the controversial topic of criminal and antisocial behavior. It synthesizes findings from behavioral and population genetics, evolutionary biology and criminol …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Growth Factors as Drugs for Neurological and Sensory Disorders
Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye …
PDF
английский
DRM
€121.99
Derek J. Chadwick & Jamie A. Goode: P2 Purinoceptors
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregu …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: The Nature and Origin of Amyloid Fibrils
Amyloid fibrils are associated with a range of pathological disorders including Alzheimer’s Disease, Down’s syndrome, diabetes, cardiomyopathies, and transmissible spongiform encephalopathies. This v …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Evolution of Hydrothermal Ecosystems on Earth (and Mars?)
This book explores the possibility that life exists on Mars. It provides an interdisciplinary overview of the early evolution of life in hydrothermal ecosystems on Earth, focusing on the problem of r …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: The Molecular Basis of Cellular Defence Mechanisms
The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the ‘property’ of immunologists, the mole …
PDF
английский
DRM
€121.99
Derek J. Chadwick & Jamie A. Goode: Antibiotic Resistance
Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in an …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: Precision Agriculture
This book investigates new agricultural systems such as organic and green manuring, as well as integrated pest management practices, and looks at how they can improve farm productivity against the en …
PDF
английский
DRM
€121.19
Gregory R. Bock & Jamie A. Goode: Plasminogen-Related Growth Factors
A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic …
PDF
английский
DRM
€121.99
Gregory R. Bock & Jamie A. Goode: The Limits of Reductionism in Biology
A comprehensive volume examining the fundamental questions raised by reductionists’ theory about levels of explanation necessary to understand biological systems. The book evaluates the enormously po …
PDF
английский
DRM
€108.99
Gregory R. Bock & Jamie A. Goode: Immunological Tolerance
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and …
PDF
английский
DRM
€108.99
Derek J. Chadwick & Jamie A. Goode: Alcohol and Cardiovascular Disease
Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together much new and exciting work in this area, it reviews …
PDF
английский
DRM
€108.99
Gregory R. Bock & Jamie A. Goode: Sensory Guidance of Movement
Sensory Guidance of Movement Chairman: Mitchell Glickstein, 1998 In the past few years there has been an increasing recognition of the multiplicity of sensory and motor areas of the cerebral cortex. …
PDF
английский
DRM
€108.99
Gregory R. Bock & Jamie A. Goode: Environmental Statistics
Environmental statistics is a rapidly growing discipline that is important not only as a division of professional and academic statistics, but also in the accumulation of data on environmental effect …
PDF
английский
DRM
€108.99
Derek J. Chadwick & Jamie A. Goode: Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and pat …
PDF
английский
DRM
€163.99
Ikuo Takeuchi & Gregory R. Bock: Rhodopsins and Phototransduction
Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the vis …
PDF
английский
DRM
€108.99
Jamie A. Goode & Derek J. Chadwick: Rice Biotechnology
Rice is the most important food crop for half the world’s population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Defining Optimal Immunotherapies for Type 1 Diabetes
* This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). * Brings together contributions from the leaders …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Mitochondrial Biology
With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial re …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Growth Factors and Psychiatric Disorders
The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes wit …
PDF
английский
DRM
€163.99
Jamie A. Goode & Derek J. Chadwick: The Biology of Extracellular Molecular Chaperones
The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Novel and Re-emerging Respiratory Viral Diseases
The past decade has seen mounting global concern regarding viral outbreaks such as SARS, avian influenza and West Nile virus. In 2004 and 2005, reports of bird-to-human, and possible human-to-human, …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Role of the Sarcoplasmic Reticulum in Smooth Muscle
Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertens …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Cancer and Inflammation
Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: ‘In Silico’ Simulation of Biological Processes
Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictu …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Mucus Hypersecretion in Respiratory Disease
A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecretion. Following damage to the airway epithelium, …
PDF
английский
DRM
€149.99
Gregory R. Bock & Jamie A. Goode: Anaphylaxis
Anaphylaxis is an immediate-type allergic reaction involving the whole organism. It is the most life-threatening allergic condition. Although there are few exact epidemiological data regarding preval …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Jamie A. Goode: Mammalian TRP Channels as Molecular Targets
This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It covers the structure, function and regulation of ma …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Reversible Protein Acetylation
A comprehensive review of recent work on chromatin and non-histone proteins, this book arises from the interactions of a multidisciplinary group of scientists involved in the study of acetylation. Th …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Tissue Engineering of Cartilage and Bone
Tissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings toget …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Jamie A. Goode: Osteoarthritic Joint Pain
Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the qualit …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Development of the Cardiac Conduction System
The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias an …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Jamie A. Goode: Pathological Pain
This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: Autism
This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a d …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: Biology of IGF-1
An invaluable book containing a series of interdisciplinary discussions between clinical and basic scientists. Biology of IGF-1: Its interaction with insulin and health and malignant states focuses o …
PDF
английский
DRM
€149.99
Derek J. Chadwick & Jamie A. Goode: Mechanisms and Biological Significance of Pulsatile Hormone Secretion
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage include …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Neuronal and Cognitive Effects of Oestrogens
Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role …
PDF
английский
DRM
€161.99
Derek J. Chadwick & Jamie A. Goode: Neural Transplantation in Neurodegenerative Disease
The field of neural transplantation is at a crucial stage in its development, with results of important clinical trials on transplantation in patients with Parkinson’s disease expected soon and novel …
PDF
английский
DRM
€161.99
Gregory R. Bock & Jamie A. Goode: The Nature of Intelligence
Evolutionary psychology ans behaviour genetics are two successful and important fields in the study of human behaviour, but practitioners in these two fields have different conceptions of the nature …
PDF
английский
DRM
€171.99
Gregory R. Bock & Jamie A. Goode: Generation and Effector Functions of Regulatory Lymphocytes
Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed ‘suppressor cells’. Many recent reports have documented their existence, effect …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: Fatty Acid and Lipotoxicity in Obesity and Diabetes
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentratio …
PDF
английский
DRM
€163.99
Gregory R. Bock & Jamie A. Goode: Cortical Development
To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timel …
PDF
английский
DRM
€161.99
Gregory R. Bock & Dalia Cohen: From Genome to Therapy
This important and exciting work brings together a high-calibre group of experts to discuss the practical application of genomic information to the development of drugs. Recent technological advances …
PDF
английский
DRM
€200.70
