Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective m RNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of m RNA and viral RNA as another example of subcellular RNA kinesis.
Dietmar Richter
Cell Polarity and Subcellular RNA Localization [PDF ebook]
Cell Polarity and Subcellular RNA Localization [PDF ebook]
Acquista questo ebook e ricevine 1 in più GRATIS!
Lingua Inglese ● Formato PDF ● ISBN 9783540400257 ● Editore Dietmar Richter ● Casa editrice Springer Berlin Heidelberg ● Pubblicato 2012 ● Scaricabile 3 volte ● Moneta EUR ● ID 6318057 ● Protezione dalla copia Adobe DRM
Richiede un lettore di ebook compatibile con DRM