Autore: F. Melchers

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The study of the genetic regulation of immune response to natural multidetermi- nant immunogens was undertaken by the method of bidirectional selective breed- ing of High or Low antibody responder li …

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Several discoveries are noteworthy for allowing us to probe the recesses of the virus- infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiolog …

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For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblas …

Binding of various ligands (hormones, neurotransmitters, immunological stimuli) to membrane receptors induces the following changes: 1. Receptor redistribution (clustering, "capping") 2. Co …

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and how the known vertebrate homologues of these genes are expressed normally in differentiation and proliferation pathways as well as abnormal- ly in well-defined lymphomagenic and other oncogenic p …

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The cells of the immune system generate a large variety of binding sites which differ in their binding specificities and can therefore react specifically with a large variety of ligands. These bindin …