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The Genetics of Alzheimer’s Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer’s Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that Mediate A? Induced Neuronal Dysfunction.- Beta Amyloid and Excitatory Synapses.- A? Degradation.- Role of A ? Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease.- Tau Gene Mutations in FTDP-17 Syndromes.- Animal Models of Tauopathy.- Tau and Axonal Transport.- Growth Factors in Alzheimer’s Disease.
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Bahasa Inggeris ● Format PDF ● Halaman-halaman 286 ● ISBN 9780387351353 ● Saiz fail 3.5 MB ● Penyunting Sangram S. Sisodia & Rudolph E. Tanzi ● Penerbit Springer US ● Bandar raya NY ● Negara US ● Diterbitkan 2007 ● Muat turun 24 bulan ● Mata wang EUR ● ID 2144943 ● Salin perlindungan Social DRM
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