After the discovery of endogenous NO formation in the late ’80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/s GC interaction and c GMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (c GMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/s GC interactions, c GMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel c GMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Harald H. H. W. Schmidt & Franz B. Hofmann
cGMP: Generators, Effectors and Therapeutic Implications [PDF ebook]
cGMP: Generators, Effectors and Therapeutic Implications [PDF ebook]
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Język Angielski ● Format PDF ● Strony 583 ● ISBN 9783540689645 ● Rozmiar pliku 11.1 MB ● Redaktor Harald H. H. W. Schmidt & Franz B. Hofmann ● Wydawca Springer Berlin ● Miasto Heidelberg ● Kraj DE ● Opublikowany 2008 ● Do pobrania 24 miesięcy ● Waluta EUR ● ID 2162909 ● Ochrona przed kopiowaniem Społeczny DRM