This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.
Tabela de Conteúdo
Chapter 1. Fungal Endophytes as Novel Sources of Anticancer Compounds.- Chapter 2. Gastrointestinal Bezoar Stones: Current Knowledge and Future Pperspective on the Potential of Plant-derived Phytobezoar in Cancer Treatment.- Chapter 3. Potential of Natural Products for Prevention of Oral Cancer.- Chapter 4. Therapeutic Potential of Cardiac Glycosides Against Cancer.- Chapter 5. Conserving Biodiversity of a Potent Anticancer Plant, Catharanthus roseus Through In vitro Biotechnological Intercessions: Substantial Progress and Imminent Prospects.- Chapter 6. Medicinal Plants as a Potential Source of Chemopreventive Agents.- Chapter 7. Plant Metabolites as New Leads to Anticancer Drug Discovery: Approaches and Challenges.- Chapter 8. Terpenes of Genus Salvia: Cytotoxicity and Antitumoral Effects.- Chapter 9. Essential Oil with Anticancer Activity: An Overview.- Chapter 10. Fungal Endophytes from Anticancer Plants as Producers of the Anti-tumour Agent L-Asparaginase: A Look at Diversity, Ubiquity and Enzyme Production.- Chapter 11. Xylooligosaccharides and their Anticancer Potential: An Update.- Chapter 12. Phytochemicals Targeting Endoplasmic Reticulum Stress to Inhibit Cancer Cell Proliferation.- Chapter 13. Remedy of Targeting Cancer and Ccancer Stem Cells with Botanicals.- Chapter 14. Therapeutic Strategies of Natural Agents and its Components on Triple-Negative Breast Cancer.- Chapter 15. Endophytic Microbes as a Novel Source for Producing Anticancer Compounds as Multidrug Resistance Modulators. Chapter 16. Traditional Medicinal Plants and their Therapeutic Potential Against Major Cancer Types.- Chapter 17. Platelet Derived Growth Factor Receptor (PDGF-R) as the Target for Herbal Based Anticancer Agents.- Chapter 18. Plant Cell and Organ Culture as an Alternative for the Production of Anticancer Compounds.- Chapter 19. Plant Derived Extracts and Compounds: An Alternative Therapy Against Breast Cancer.- Chapter 20. Micropropagation and Conservation of Selected Endangered Anticancer Medicinal Plants from the Western Ghats of India.- Chapter 21. Biotechnological Approaches for the Propagation of Anticancer Plants and the Production of Vital Compounds.- Chapter 22. An Alternative Approach for Anticancer Compounds Production Through Plant Tissue Culture Techniques.- Chapter 23. Biotechnological Intervention Through Tissue Culture in Hedychium coronarium: A Potential Anticancer Plant.
Sobre o autor
Dr. Mohd. Sayeed Akhtar, is working as a Assistant Professor in Gandhi Faiz-e-Aam College, Shahjahanpur, U.P., India. He has received his Ph D degree from Aligarh Muslim University (AMU), India in 2008. He has conducted his postdoctoral research at the Botanical Institute, University of Basel (BIB), Switzerland (2008-2010) and Chonbuk National University (CBNU), Republic of Korea in 2011, respectively, and also works Assistant Professor, Department of Biology, College of Natural Sciences, Jimma university, Jimma, Ethiopia form 2011-2014, and Fellow Researcher UDQ9 at the Institute of Tropical Agriculture, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia (2014-2015). Dr. Akhtar has 14 years of research and 8 years teaching experience in Soil Microbiology, Applied Microbiology, Environmental Microbiology, Molecular Biology, Plant Pathology and Plant Nano-biotechnology. Dr. Akhtar has received several prestigious fellowships at National and International levels till date. His promising approach and dedication stands him in the row of foremost scientist in the field of Plant-Microbe Interaction and Plant Nano-biotechnology. He is author and co-author of more than hundred articles in peer reviewed journals, conference proceedings and book chapters in the books published by Springer-Verlag and also edited 6 books with international publishers. He is serving the scientific community as editorial board member and reviewer of several high impact international Journals. His current research is focused on the rhizospheric plant-microbe interactions and their molecular biotechnology, bioremediation, biomineralization, nanofertilizers and Nanobiotechnology.
Dr. Mallappa Kumara Swamy, is presently a Postdoctoral Researcher at the Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia. Dr. Swamy has obtained his Ph D (Biotechnology) from Acharya Nagarjuna University, Guntur, India in 2013.He has more than 14 years of teaching and research experience in the fields of plant biotechnology, secondary metabolites production, phytochemistry and bioactive studies. To his credit, Dr. Swamy has published more than 50 research publications in peer- reviewed journals. Dr. Swamy is also the editorial board member and reviewer of several high impact international journals. Dr. Swamy is presently engaged in cell and tissue culture technology for bioactive compounds production and their bioactivities studies. Also, his research focuses on nanotechnology for medical applications.
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