Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences.
Cuprins
Contributors.
Preface.
SECTION I: EPIGENETICS AND CELL CYCLE.
1 Epigenetic Modulation of Cell Cycle: An Overview (Micaela
Montanari, Antonio Giordano, Marcella Cintorino, and Marcella
Macaluso).
SECTION II: EPIGENETICS AND CELL DEVELOPMENT, SENESCENCE AND
DIFFERENTIATION.
2 Epigenetics in Skeletal Muscle Development (Cristina
Giacinti and Antonio Giordano).
3 Epigenetic Control in Cellular Senescence (Heike Helmbold,
Wolfgang Deppert, and Wolfgang Bohn).
4 Epigenetic Modulation in Cell Development and Differentiation
(Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata
Vocca, and Francesca Pentimalli).
SECTION III: EPIGENETICS AND GENE TRANSCRIPTION.
5 Epigenetic Control of Gene Transcription (Christian
Bronner, Mayada Achour, Thierry Chataigneau, and Valerie B.
Schini-Kerth).
6 Epigenetics, Micro RNAs, and Cancer: An Update (Giuseppe
Russo, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia
Cito, Debora Muresu, Flavio Rizzolio, and Antonio
Giordano).
SECTION IV: EPIGENETICS AND CANCER.
7 The Role of Epigenetic Modifications in Cancer (Michael J.
Powell, Vladimir M. Popov, Xiang Wang, Steven B. Mc Mahon, Alexander
Mazo, and Richard G. Pestell).
8 MBD4/MED1 Protein in DNA Repair and Demethylation, Cancer, and
Other Diseases (Serena Buontempo, Mara Sannai, and Alfonso
Bellacosa).
9 Epigenetics in Pediatric Cancers (Roberta Ciarapica,
Lavinia Raimondi, Federica Verginelli, and Rossella Rota).
10 Epigenetic Mechanisms in Cancer Formation and Progression
(Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia
Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral,
and Michele Maio).
SECTION V: EPIGENETICS AND ANTICANCER DRUG DEVELOPMENT AND
THERAPY.
11 Recent Advances in the Field of Stem Cell Research: Toward
the Definition of the Epigenetic and Genetic Codes of Pluripotency
(Gaetano Romano).
12 Potential of Heat Shock Protein Targeting for Human Therapy
(Laszlo Otvos, Jr).
13 Advances in Stem Cell Therapy for Cancer Research (Andrew
Puca and Antonio Giordano).
14 Epigenetic Targets and Drug Development (Paraskevi
Vogiatzi, Maria Irene Scarano, and Pier Paolo Claudio).
Index.
Despre autor
Antonio Giordano, M.D., Ph. D., is professor of biology and
medical research at Temple University College of Science and
Technology in Philadelphia, Pennsylvania. In 1993 he co-founded the
Sbarro Institute for Cancer Research and Molecular Medicine. He has
been honored as Knight by the president of Italy and is recipient
of the National Italian-American Political Action Committee
(NIA-PAC) National Lifetime Achievement Award in Medical Research.
Marcella Macaluso, Ph.D., is associate professor of
biology and a researcher in the Hormone-Signaling and Cancer
Program of the Sbarro Institute for Cancer Research at Temple
University in Philadelphia.
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