This is the only advanced practice guide to provide an overview of the major DSM-5 disorders across the lifespan and complete clinical guidelines for their psychopharmacologic management. It has been compiled by expert practitioners in psychiatric care and is designed for use by nurse practitioners and other primary caregivers in clinical practice.
The guide is organized in an easy-to-access format with disorders for which drugs can play a significant therapeutic role. The listing for each disorder includes clinical features and symptoms, as well as information about the most current and effective drugs for management. A clearly formatted table identifies the first and second lines of drug therapy along with adjunctive therapies for each disorder. Drugs are organized according to classification, and each listing provides the essential information needed to safely prescribe and monitor a patient’s response to a particular drug. Brand and generic names, drug class, customary dosage, side effects, drug interactions, pharmacokinetics, precautions, and management of special populations are addressed. Convenient, practical, and portable, this guide will be a welcome and frequently used resource.
Key Features:
- Presents psychopharmacological treatment guidelines for major DSM-5 disorders and parameters for use of each drug
- Prioritizes drugs according to their clinical efficacy and recommended treatment algorithms
- Includes brand and generic names, customary dosages, side effects, drug interactions, pharmacokinetics, precautions, and management of special populations
- Provides easy-to-read tables for quick clinical consultation
- Offers information on clinical algorithms, lab evaluation, and preventive services
Cuprins
Contributors xiii
Preface xvii
Acknowledgments xix
Part I. General Psychiatry
1. The Psychiatric Interview and Diagnosis 3
2. Psychotherapeutic Management 19
3. Behavioral Therapy, Cognitive Behavioral Therapy, and Psychoanalysis 25
Part II. Principles of Clinical Psychopharmacology
4. Clinical Neuroanatomy of the Brain 41
5. The Relationship of Psychopharmacology to Neurotransmitters, Receptors, Signal Transduction, and Second Messengers 51
6. Principles of Pharmacokinetics and Pharmacodynamics
7. Principles and Management of Psychiatric Emergencies 69
Part III. Syndromes and Treatments in Adult Psychiatry*
8. Behavioral and Psychological Disorders in the Elderly 81
9. Substance Use Disorders 93
10. Psychotic Disorders 111
11. Mood Disorders 143
12. Anxiety Disorders 187
13. Somatic Symptom and Related Disorders 219
14. Dissociative Disorders 227
15. Sexual Dysfunction 241
16. Paraphilic Disorders 257
17. Feeding and Eating Disorders 265
18. Personality Disorders 285
19. Sleep Disorders 299
Part IV. Syndromes and Treatments in Child and Adolescent Psychiatry*
20. Disorders Presenting in Infancy or Early Childhood (0–5 Years of Age) 317
21. Disorders Presenting in Middle Childhood (6–11 Years of Age) or Adolescence (12–18 Years of Age) 361
Part V. Drug Monographs
Alprazolam (Xanax/Xanax XR/Niravam; also Apo-Alpraz, Apo-Alpraz TS, Novo-Alprazol, Nu-Alpraz) 391
Amitriptyline Hydrochloride (Elavil) 394
Aripiprazole (Abilify, Abilify Discmelt, Abilify Maintena) 398
Armodafinil (Nuvigil) 401
Asenapine (Saphris) 404
Atomoxetine Hydrochloride (Strattera) 407
B Complex (Vitamin B1 /Thiamine Hydrochloride) 409
Bismuth Subsalicylate 410
Bromocriptine Mesylate (Parlodel, Cycloset) 412
Buprenorphine, Buprenorphine HCl, Buprenex, Butrans, and Naloxone HCl Dihydrate (Subutex, Suboxone) 415
Buprenorphine/Naloxone (Suboxone) 418
Bupropion (Wellbutrin, Bupropion Hydrobromide [Aplenzin]), and Bupropion Hydrochloride (Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban) 421
Carbamazepine (Tegretol, Carbatrol, Teril, Tegretol XR, Equetro) 424
Chlordiazepoxide Hydrochloride (Librium) 428
Citalopram Hydrochloride (Celexa) 430
Clomipramine (Anafranil) 433
Clonazepam (Klonopin) 436
Clonidine Hydrochloride (Catapres, Dixarit, Duraclon, Jenloga, Kapvay, Catapres-TTS) 438
Clorazepate (Tranxene) 440
Clozapine (Clozaril, Fazaclo) 442
Cyclobenzaprine (Flexeril) 446
Cyproheptadine (Periactin) 448
Desipramine (Norpramin) 449
Desvenlafaxine (Pristiq) 451
Dexmethylphenidate (Focalin) 454
Dextroamphetamine and Amphetamine (Adderall) 456
Diazepam (Valium) 459
Dicyclomine (Bentyl) 461
Diphenhydramine Hydrochloride (Benedryl) 463
Divalproex Sodium (Depacon, Depakene, Depakote, Depakote ER, Depakote Sprinkle) 466
Donepezil Hydrochloride (Aricept) 469
Doxepin (Sinequan, Silenor) 471
Duloxetine (Cymbalta) 473
Escitalopram (Lexapro) 476
Eszopiclone (Lunesta) 479
Fluoxetine Hydrochloride (Prozac) 481
Fluoxetine Maleate (Luvox, Luvox CR) 485
Fluphenazine, Fluphenazine Hydrochloride (Modecate, Modecate Concentrate), Fluphenazine Decanoate (Prolixin) 489
Flurazepam (Dalmane, Dalmadorm) 492
Galantamine Hydrobromide (Razadyne, Razadyne ER) 494
Guanfacine Hydrochloride (Intuniv, Tenex) 496
Haloperidol Decanoate, Haloperidol Lactate (Haldol) 498
Hydroxyzine Hydrochloride (Atarax, Vistaril), Hydroxyzine Pamoate (Vistaril) 501
Ibuprofen (Motrin) 503
Iloperidone (Fanapt) 505
Imipramine (Tofranil) 507
Isocarboxazid (Marplan) 510
Lamotrigine (Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR) 512
Levomilnacipran (Fetzima) 514
Lisdexamfetamine Dimesylate (Vyvanse) 516
Lithium Carbonate, Lithium Citrate (Cibalith-S, Eskalith, Lithobid) 518
Loperamide (Imodium) 521
Lorazepam (Ativan) 523
Lurasidone Hydrochloride (Latuda) 526
Memantine Hydrochloride (Namenda, Namenda XR) 528
Methadone Hci (Methadose Oral Concentrate) 530
Methadone Hci (Methadose Oral Concentrate, Dolophine, Methadose) 532
Methocarbamol (Robaxin) 534
Methylphenidate (Methylin) 537
Methylphenidate Transdermal (Methylphenidate Hydrochloride, Concerta, Metadate CD, Metadate ER, Methylin ER, Ritalin, Ritalin LA, Ritalin SR, Daytrana Patch) 540
Midazolam Hydrochloride (Versed) 543
Mirtazapine (Remeron, Also Remeron Soltab) 546
Modafinil (Provigil) 549
Modafinil (Provigil, Alert-C) 551
Naloxone Hydrochloride (Narcan) 553
Naltrexone (Revia, Vivitrol) 555
Nicotine (Nicotrol NS, Nicotrol Inhaler, Commit, Habitrol, Nicoderm, Nicotrol Prostep, Nicorette Gum, Nicorette DS), Varenicline (Chantix) 559
Nortriptyline Hydrochloride (Pamelor, Aventyl) 561
Olanzapine (Zyprexa, Zyprexa Zydis), Olanzapine Pamoate (Zyprexa Relprevv) 564
Oxazepam (Serax) 567
Oxcarbazepine (Carbatrol) 569
Perphenazine (Trilafon) 573
Phenobarbital 575
Quetiapine Fumarate (Seroquel, Seroquel XR) 578
Risperidone (Risperdal, Risperdal M-Tab, Risperdal Consta) 582
Rivastigmine Tartrate (Exelon, Exelon Patch) 587
Sertraline Hydrochloride (Zoloft) 589
Tacrine Hydrochloride (Cognex) 593
Temazepam (Restoril) 595
Thioridazine Hydrochloride (Mellaril) 597
Thiothixene (Navane) 600
Trazodone Hydrochloride (Desyrel, Oleptro) 602
Triazolam (Halcion) 604
Zaleplon (Sonata) 606
Ziprasidone (Geodon) 608
Zolpidem (Ambien) 611
Zonisamide (Zonegran) 613
Index 615
Despre autor
Patrick J. M. Murphy, Ph D, is an Assistant Professor at the Seattle University College of Nursing.