This volume includes nine chapters that detail advances in health and disease. In chapter one the authors review proteins and transcription factors involved in the process of EMT and analyze the potential of proved or non-proved phytodrug to inhibit resistance to conventional therapies and /or metastasis, emphasizing their specificity. Chapter two provides an overview of the knowledge gained so far concerning the role of different members of phosphodiesterases subfamilies under physiological, as well as pathological conditions. In chapter three the authors discuss the involvement of IL-9 and Th9 cells in various cancers, highlighting their role in cancer immunity. The authors in chapter four identifiy the prospects for using drugs with anticonvulsant action that primarily restricts neuronal excitation via modulation of the brain’s functional neurovascular unit. In chapter five, the authors propose a novel method for calculating (possibly multiple) univariate scores per individual to identify disease subtypes using multiple brain images (multi-modal brain images) obtained from multiple measurement or processing methods. Chapter six provides a detailed introduction of cognitive rehabilitation, presents the history and types of theories in this field, and then reviews studies that have recently used cognitive rehabilitation methods in different samples of patients and types of disorders and have reported the efficacy of these intervention methods. The causes, molecular mechanisms, and the diagnosis and treatment of prostate benign hyperplasia is examined in chapter seven. In chapter eight a model of a virus attacking a cell is proposed from the standpoint of sorption processes of cytoplasmic nucleotides, as a resource of both genomes. Using the method of gravitational non-invasive mass spectroscopy (GMS), the conformational state and the mechanism of action of domains in the myosin heads of the eye muscles of probants of different ages are studied in chapter nine.
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