Michael Strauss & John A. Barranger 
Concepts in Gene Therapy [PDF ebook] 

Frontmatter – Preface – Contents – I. Methods of Gene Delivery – 1. Retroviral Vectors – 2. Adenoviral Vectors – 3. Herpes Simplex Virus Mediated Gene Transfer to Neurons – 4. Adeno-Associated Viral Vectors – 5. Virus Functions for Artificial Vectors – 6. Targeted Gene Delivery and Expression in Hepatocytes – 7. Particle-Mediated Gene Delivery System for Cancer Research – II. Methods for Inactivation or Restoration of Gene Function – 8. Gene Inactivation by Homologous Recombination – Animal Models of Plasma Lipoprotein Disorders – 9. Potential Antisense Oligonucleotide Therapies for Neurodegenerative Diseases – 10. Synthetic Ribozymes: The Hammerhead Ribozyme – 11. Ribozymes as Tools for the Gene Therapist – III. Cellular Target Systems – 12. Gene Transfer and Transgene Expression in Hematopoietic Cells – 13. The Liver as a Target for Gene Therapy – 14. Gene Therapy for Gaucher Disease via Genetically Engineered Primary Myoblasts – 15. In vivo Secretion of Therapeutic Proteins from Neo-Organs – IV. Genetic Diseases – 16. Gene Therapy for Cystic Fibrosis – Strategies, Problems and Perspectives – 17. Gene Therapy for Dystrophin Deficiency – 18. Gene Therapy For Familial Hypercholesterolemia – 19. Therapeutic Strategies for the Lysosomal Storage Disorders – V. Non-Genetic and Infectious Diseases – 20. Gene Therapy for Arthritis – 21. Gene Therapy for HIV-1 Disease – VI. Cancer – 22. Suicide Genes for the Treatment of Cancer – 23. Tumor Cell Vaccines Using Genetically Modified Cells Coexpressing Cytokines and the T Cell Costimulatory Molecule B7 – 24. Dosage Impact on Immunotherapy with Cytokine-Gene Modified Cancer Vaccines – 25. Tumor Suppressor Gene Therapy – Growth Arrest and Programmed Cell Death – Acknowledgement – References – Contributors – Index