Sarcoma Oncology: A Multidisciplinary Approach is a comprehensive textbook that addresses the entire spectrum of the subject from epidemiology to laboratory research in the biology of sarcomas.
Chapters contributed by an international group of highly regarded specialists cover the epidemiology and pathology of sarcomas; diagnostic imaging and biopsy techniques; staging and prognosis: surgery of sarcomas in extremity soft tissue, abdominal wall and trunk, and skeletal bone; hyperthermia in sarcoma treatment; isolated limb perfusion; surgery for metastases; reconstructive surgery; radiation therapy; systemic chemotherapy; multidisciplinary care; treatment-induced sarcoma; pain management in sarcoma; and basic research including molecular biology and mouse models.
Cuprins
SECTION 1. OVERVIEW: EPIDEMIOLOGY, PATHOLOGY, IMAGING, STAGING, AND PROGNOSIS
Ch 1 Environmental and Inherited Risk Factors in Sarcomas by D. M. Thomas, M.L. Ballinger
Ch 2 Introduction to Pathology by Ghadah A. Al Sannaa, Alexander J. Lazar
Ch 3 Pathology of Soft Tissue Tumors by Ting Liu, Krisha K. Narra, Phillip D. Stephenson, Allie H. Grossman, Erinn Downs-Kelly, Daniel Albertson
Ch 4 Pathology of Bone Sarcoma by Yaxia Zhang, Andrew E. Rosenberg
Ch 5 Bone and Soft Tissue Tumors: Contemporary Imaging by Rajendra Kumar, John E. Madewell
Ch 6 PET Imaging of Mesenchymal Tumors by Christopher J. Hanrahan, John M. Hoffman
Ch 7 Traditional Size-Based Response Evaluation Criteria in Solid Tumors and New Evidence-Based Response Evaluation Criteria (Choi Criteria) in Sarcoma by Haesun Choi
Ch 8 Biopsy Techniques by Sandra L. Wong, Sha’Shonda L. Revels
Ch 9 Soft Tissue Sarcoma Staging and Nomograms by Paxton V. Dickson, Daniel A. Anaya
SECTION 2. SARCOMA TREATMENT MODALITIES
Ch 10 Sarcoma Surgery: Purpose and Role Relationship to Other Modalities by Geoffrey W. Siegel, J. Sybil Biermann
Ch 11 Margins and Sarcoma Resections—What is Marginal? by Valerae O. Lewis
Ch 12 Surgery of Abdominal Wall and Trunk Sarcoma by Chiara Colombo, Marco Fiore, Alessandro Gronchi
Ch 13 Surgical Management of Upper Extremity Bone Sarcomas by Tessa Balach, Terrance D. Peabody
Ch 14 Surgical Management of Lower Extremity Bone Sarcomas by Nader Nassif, David Mc Keown, Nicola Fabbri
Ch 15 Surgical Management of Spinal Sarcoma by Sherise D. Ferguson, Claudio E. Tatsui, Laurence D. Rhines
Ch 16 Surgical Treatment of Pelvic Bone Sarcomas by Andreas F. Mavrogenis, Andrea Angelini, Elisa Pala, R. Lor Randall, Pietro Ruggieri
Ch 17 Isolated Limb Perfusion with Melphalan and TNF-a in the Treatment of Extremity Sarcoma by Cornelis Verhoef, Alexander M.M. Eggermont
Ch 18 Surgical Treatment of Sarcomatous Lung Metastases by Costas S. Bizekis, Joseph B. Levin, Harvey I. Pass
Ch 19 Composite Tissue Reconstruction after Sarcoma Resection by Donald P. Baumann, Justin M. Sacks
Ch 20 External Beam/Intensity Modulated Radiotherapy by Colleen Dickie, Brian O’Sullivan, Charles Catton, Peter Chung, Amy Parent
Ch 21 Intraoperative Irradiation by Brian G. Czito, Christopher G. Willett
Ch 22 Soft Tissue Sarcoma Brachytherapy by Martine Delannes
Ch 23 Particle Beam Therapy for Sarcoma by William P. Levin, Eugen Hug, Thomas F. De Laney
Ch 24 Hyperthermia in Sarcoma Treatment by Lars H. Lindner, Rolf D. Issels
Ch 25 Chemotherapy for Soft Tissue Sarcomas: Contemporary Approaches by Vinod Ravi, Shreyashkumar Patel
Ch 26 Personalized Molecular Therapeutics for Sarcomas by Lisa Abegglen, Michael Black, Jamie Gardiner, Joshua D. Shiffman
Ch 27 Sarcomas of the Breast by Karim Boudadi, Rashmi Chugh
Ch 28 Sarcomas of the Head and Neck by Fernando Gomez-Rivera, Thomas D. Shellenberger, Erich M. Sturgis
SECTION 3. MULTIDISCIPLINARY CARE
Ch 29 Genitourinary Sarcomas by Charles Catton, Rebeccca Gladdy, Karosh Kalili
Ch 30 Multidisciplinary Management of Retroperitoneal Sarcoma and Relapse by J. Harrison Howard
Ch 31 Sarcoma of the Heart and Great Vessels by Tsuyoshi Kaneko, Ara A. Vaporciyan, Shanda H. Blackmon, Michael J. Reardon
Ch 32 Chest Wall Sarcoma by Robert E. Merritt
SECTION 4. SPECIFIC HISTOLOGIES
Ch 33 Desmoid Tumors: A Treatment Algorithm According to Biological Behavior? by Sylvie Bonvalot, Anant Desai, Sarah Copppla, Cécile Le Péchoux, Philippe Terrier, Julien Dômont, Axel Le Cesne
Ch 34 Dermatofibrosarcoma Protuberans by Scott M. Schuetze, Christopher K. Bichakjian, David R. Lucas
Ch 35 Kaposi’s Sarcoma by Mordechai Gutman
Ch 36 Gastrointestinal Stroma Tumor: Contemporary Understanding and Management by M. von Mehren, D. Flieder, L. Rink, J. C. Watson
Ch 37 Biology of GIST by Lori Rink, Andrew K. Godwin
Ch 38 Medical Management and Treatment of Recurrent Gastrointestinal Stromal Tumor by Ernesto Bustinza-Linares, Gabriel Tinoco, Jonathan C. Trent
Ch 39 Surgical Management of Gastrointestinal Stromal Tumor (GIST) by Vinod P. Balchandran, Ronald P. De Matteo
Ch 40 Malignant Peripheral Nerve Sheath Tumor by Keluo Yao, Jason Payne, Thomas J. Scharschmidt, Arvinder Bhinder, Hans Iwenofu
Ch 41 Osteosarcoma: A Multidiscplinary Approach by David S. Geller, Jonathan B. Gill, Beverly A. Thornhill, Marnee Spierer, Richard Gorlick
Ch 42 Ewing Sarcoma Family of Tumors by Paul A. Meyers
Ch 43 Chondrosarcoma by Francis J. Hornicek
Ch 44 Chordoma by Francis J. Hornicek
Ch 45 Rhabdomyosarcoma by Douglas S. Hawkins
Ch 46 Liposarcoma by Philip Wong, Peter Chung
Ch 47 Leiomyosarcoma by Andrew L. Folpe
Ch 48 Undifferentiated Pleomorphic Sarcoma or Malignant Fibrous Histiocytoma by Keila E. Torres, Peter W.T. Pisters
Ch 49 Angiosarcoma by Vinod Ravi, Shreyaskumar Patel
Ch 50 Hemangioendothelioma by William W. Tseng, John E. Madewell, Jeanne M. Meis
Ch 51 Solitary Fibrous Tumors in the Twenty-First Century: a Clinical and Pathologic Update by Cheryl M. Coffin, Vicki L. Keedy, Ginger E. Holt
Ch 52 Clear Cell Sarcoma by Franz O. Smith, Marilyn M. Bui, Ricardo J. Gonzalez, Vernon K. Sondak
Ch 53 Alveolar Soft Part Sarcoma by Daniel E. Abbott, Raphael E. Pollock
Ch 54 Synovial Sarcoma by Kevin B. Jones
Ch 55 Epithelioid Sarcoma by Bartosz Chmielowski, William D. Tap
SECTION 5. RELAPSED SARCOMA
Ch 56 Treatment-Induced Sarcoma Soft Tissue and Bone Sarcomas by Benjamin Chua, Sandro V. Porceddu
Ch 57 Locally Recurrent Extremity Soft Tissue Sarcoma by Peter C. Ferguson
SECTION 6. ADDITIONAL CONSIDERATIONS
Ch 58 Chemotherapy for Palliation by Andrea Marrari, Andrew J. Wagner
Ch 59 Palliative Care for Advanced Sarcoma Patients by Maria J. Silviera
Ch 60 Palliation for Soft Tissue Sarcomas by Tom Scharschmidt, Ravi Chokshi, William Kraybill
Ch 61 Cost-Effective Patient Surveillance after Sarcoma Treatment by David Y. Johnson, Frank E. Johnson
Ch 62 Sarcoma Survivors by Melinda S. Merchant, Crystal L. Mackall
Ch 63 Long-term Consequences of Systemic Therapies in Sarcoma by Andrea Marrari, Suzanne George
Ch 64 Long-term Complications Associated with Radiation Therapy in Soft Tissue Sarcoma Management by Hadley J. Sharp, B. Ashleigh Guadagnolo
Ch 65 Outcome Measures in Musculoskeletal Oncology by Anthony Griffin
Ch 66 Patient Advocacy in Sarcoma by Bruce D. Shriver, Mary Sorens
Ch 67 The Role of the Internet in Sarcoma Care by Mary Sorens, Bruce D. Shriver
SECTION 7. LABORATORY RESEARCH
Ch 68 Sarcoma Cancer Stem Cells by Colleen Wu, James A. Kennedy, Benjamin A. Alman
Ch 69 Genetically Engineered Mouse Models of Sarcoma by Malay Haldar
Ch 70 Molecular Profiling of Sarcomas by Cheng-Han Lee, Inigo Espinosa, Xiangqian Guo, Matt van de Rijn
Ch 71 Recent Advances in the Characterization of Mesenchymal Tumors: From Sarcoma Genomics to Targeted Therapies by Rebecca Dodd, Jordi Barretina, Jonathan A. Fletcher, David Kirsch
Ch 72 Telomere Maintenance Mechanisms by Matthew J. Plantinga, Kara M. Pascarelli, Margaret von Mehren & Dominique Broccoli
Ch 73 Tumor Microenvironment Cross-talk by Kari Brewer, Keila E. Torres, Dina Lev
Despre autor
Brian O’Sullivan, MB, Bch, BAO, FRCPC, is Professor in the Department of Radiation Oncology and Professor in the Department of Otolaryngology at the University of Toronto.
Dr. O’Sullivan is also Associate Director of the Radiation Medicine Program at Princess Margaret Hospital in Toronto, Ontario, Canada.
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