Autor: Ronald Ross Watson

Ajutor
Victor R. Preedy, Ph D. DSc, PRIPH, FRSH, FIBiol, FRCPath, is Director of the Genomics Centre and Professor of Nutritional Biochemistry in the Department of Nutrition and Dietetics at King’s College London. He is on the editorial advisory board of Journal of Cellular Pathology, Frontiers in Bioscience, and Drug and Alcohol Dependence. Has published numerous peer-reviewed papers, abstracts, and reviews, as well as 15 books. Currently, he is editor-in-chief of Handbook of Disease Burdens and Quality of Life Measures, Springer 2010




92 Ebooks de Ronald Ross Watson

Victor R. Preedy & Ronald Ross Watson: Handbook of Behavior, Food and Nutrition
This book disseminates current information pertaining to the modulatory effects of foods and other food substances on behavior and neurological pathways and, importantly, vice versa. This ranges from …
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€1,165.23
Ronald Ross Watson: Functional Foods and Nutraceuticals in Cancer Prevention
Cancer is a leading cause of death among adults but research shows that the chances of developing cancer can be reduced by lifestyle changes. Increasing numbers of people use dietary vegetables, medi …
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€210.99
Ronald Ross Watson: Eggs and Health Promotion
Eggs and Health Promotion provides up-to-date research on the use of eggs in human health. This single, convenient reference deals with the role of eggs in diet, nutrition, and disease. The book also …
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€147.99
Douglas Larson & Ronald Ross Watson: Immune Dysfunction and Immunotherapy in Heart Disease
Current heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years – suggesting a failure in treating the underlying mechanism. This book propos …
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€156.99
Fabien De Meester & Sherma Zibadi: Modern Dietary Fat Intakes in Disease Promotion
The Nutrition and Health series of books have had great success because each volume has the consistent overriding mission of providing health professionals with texts that are essential because each …
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€213.99
Ronald Ross Watson & Sherma Zibadi: Dietary Components and Immune Function
Dietary Components and Immune Function focuses on immune modulation, immune mediated disease resistance, immune changes due to AIDS, immune modulated cancer therapy, and autoimmune diseases as modifi …
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€181.89
Ronald Ross Watson & Joe K Gerald: Nutrients, Dietary Supplements, and Nutriceuticals
Nutrients, Dietary Supplements, and Nutriceuticals: Cost Analysis Versus Clinical Benefits provides the most current, concise, scientific appraisal and economic analysis (costs vs. benefit) of nutrit …
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€213.99
Ronald Ross Watson & Victor R. Preedy: Chocolate in Health and Nutrition
Chocolate in Health and Nutrition represents the first comprehensive compilation of the newest data on the actions of the flavonoids and microorganisms associated with the beneficial effects of choco …
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€160.49
Ronald Ross Watson & Victor R. Preedy: Magnesium in Human Health and Disease
Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. …
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€106.99
Ronald Ross Watson & Victor R. Preedy: Alcohol, Nutrition, and Health Consequences
Chronic alcohol use is associated with heart, liver, brain, and other organ pathology.  Alcohol is a drug of abuse and a caloric food and it causes poor intake and absorption of nutrients, thus …
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€213.99
Ronald Ross Watson & Sherma Zibadi: Bioactive Dietary Factors and Plant Extracts in Dermatology
The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplement …
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€160.49
Fabien De Meester & Ronald Ross Watson: Omega-6/3 Fatty Acids
Over the last several years developing human research suggests that a component of omega-3 fatty acids, long chain ones, contribute particularly to health benefits. Omega-6/3 Fatty Acids: Functions, …
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€223.63
Ronald Ross Watson & George Grimble: Nutrition in Infancy
Nutrition in Infancy: Volume 1 is a very useful resource for all clinicians treating and preventing nutritional problems in infants.  This volume covers a wide range of topics that support welln …
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€213.99
Ronald Ross Watson & George Grimble: Nutrition in Infancy
Nutrition in Infancy: Volume 2 is a very useful resource for all clinicians treating and preventing nutritional problems in infants.  This volume covers a wide range of topics that support welln …
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€213.99
Caroline J. Hollins Martin & Ronald Ross Watson: Nutrition and Diet in Menopause
Nutrition and Diet in Menopause is a single comprehensive source that will provide readers with an understanding of menopause.  Holistic in its approach, this volume is divided into five section …
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€128.39
Ronald Ross Watson: Handbook of vitamin D in human health
Research and clinical application of vitamin D has increased dramatically over the past decade stimulated by novel health promotion discoveries and documentation. This book brings together key resear …
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€187.25
Victor R Preedy & Ronald Ross Watson: Comprehensive Handbook of Alcohol Related Pathology
This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant in …
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€533.40
Victor R Preedy & Ronald Ross Watson: Bioactive Foods in Promoting Health
While everyone knows fruits and vegetables are beneficial to good health, it’s increasingly seen as important to know which ones can be effective in treating specific illnesses. For example, which ar …
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€82.42
Gerard N. Burrow & Victor R Preedy: Comprehensive Handbook of Iodine
Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damag …
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€224.66
Ronald Ross Watson: Complementary and Alternative Therapies and the Aging Population
The major objective of this book is to review in detail health problems occurring with significant frequency in aging adults which are proposed to be treated or ameliorated using nutriceuticals as fo …
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€68.63
Victor R Preedy & Ronald Ross Watson: Olives and Olive Oil in Health and Disease Prevention
Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From car …
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€174.41
Victor R Preedy & Ronald Ross Watson: Bioactive Foods in Promoting Health
Bioactive Foods in Promoting Health: Probiotics and Prebiotics brings together experts working on the different aspects of supplementation, foods, and bacterial preparations, in health promotion and …
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€133.16
Victor R Preedy & Ronald Ross Watson: Nuts and Seeds in Health and Disease Prevention
The use of nuts and seeds to improve human nutritional status has proven successful for a variety of conditions including in the treatment of high cholesterol, reduced risk of Type-2 Diabetes, and we …
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€160.15
Vinood B. Patel & Victor R Preedy: Flour and Breads and their Fortification in Health and Disease Prevention
Bread and flour-based foods are an important part of the diet for millions of people worldwide. Their complex nature provides energy, protein, minerals and many other macro- and micronutrients. Howev …
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€160.17
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Cardiovascular Disease
One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that ox …
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€101.21
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for the Aging Population
Bioactive Food as Dietary Interventions for the Aging Population presents scientific evidence of the impact bioactive foods can have in the prevention and mediation of age related diseases. Written b …
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€101.21
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Diabetes
The role of diet in the prevention, control and treatment of diabetes continues to provide significant opportunity for non-pharmaceutical interventions for many of the over 20 million people who live …
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€101.21
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related …
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€116.60
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases
While diet has long been recognized as having potential to alleviate symptoms of inflammatory diseases including arthritis, lupus and fibromyalgia, research indicates that specific foods offer partic …
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€116.60
Victor R Preedy & Ronald Ross Watson: Polyphenols in Human Health and Disease
Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the …
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€270.93
Ronald Ross Watson: Polyphenols in Plants
Polyphenols in Plants assists plant scientists and dietary supplement producers in assessing polyphenol content and factors affecting their composition. It also aids in selecting sources and regulati …
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€99.85
Victor R Preedy & Ronald Ross Watson: Wheat and Rice in Disease Prevention and Health
Wheat and Rice in Disease Prevention and Health reviews the wide range of studies focusing on the health benefits and disease prevention associated with the consumption of wheat and rice, the two mos …
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€120.05
Ronald Ross Watson: Nutrition in the Prevention and Treatment of Abdominal Obesity
Nutrition in the Prevention and Treatment of Abdominal Obesity focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionis …
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€138.93
Victor R Preedy & Ronald Ross Watson: Mediterranean Diet
The Mediterranean Diet offers researchers and clinicians a single authoritative source which outlines many of the complex features of the Mediterranean diet: ranging from supportive evidence and epid …
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€141.45
Ronald Ross Watson: Omega-3 Fatty Acids in Brain and Neurological Health
Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to f …
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€161.12
Victor R Preedy & Ronald Ross Watson: Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease
Nutritional supplement research concerning brain health and neurological disease is becoming an important focus. While nutritional supplements are very popular for general health and well being, the …
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€158.91
Ronald Ross Watson: Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults
Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults focuses on the ways in which food and dietary supplements affect the major health problems of aging adults. Re …
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€122.16
Ronald Ross Watson: Modulation of Sleep by Obesity, Diabetes, Age, and Diet
Sleep disorder is a rampant problem in the US, with over 40 million Americans currently diagnosed according to the NIH. There is a clear association between sleep disorder and a wide range of other h …
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€161.12
Betsy Dokken & Ronald Ross Watson: Glucose Intake and Utilization in Pre-Diabetes and Diabetes
This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Gluco …
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€138.98
Ronald Ross Watson: Diet and Exercise in Cystic Fibrosis
Diet and Exercise in Cystic Fibrosis, a unique reference edited by distinguished and internationally recognized nutritionist and immunologist Ronald Ross Watson, fills the gap in the current dietary …
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€109.01
Ronald Ross Watson: Handbook of Fertility
Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive Health focuses on the ways in which food, dietary supplements, and toxic agents, including alcohol and nicotine affect the reproduct …
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€122.27
Ronald Ross Watson: Health of HIV Infected People
Health of HIV Infected People: Food, Nutrition and Lifestyle Without Antiretroviral Drugs defines the supportive roles of bioactive foods, exercise, and dietary supplements on the health of HIV infec …
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€93.87
Ronald Ross Watson: Health of HIV Infected People
Health of HIV Infected People: Food, Nutrition and Lifestyle with Antiretroviral Drugs provides basic and applied knowledge on the supportive roles of bioactive foods, exercise, and dietary supplemen …
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€93.95
Victor R Preedy & Ronald Ross Watson: Probiotics, Prebiotics, and Synbiotics
Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion reviews and presents new hypotheses and conclusions on the effects of different bioactive components of probiotics, prebiot …
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€128.56
Victor R Preedy & Ronald Ross Watson: Genetically Modified Organisms in Food
Genetically Modified Organisms in Food focuses on scientific evaluation of published research relating to GMO food products to assert their safety as well as potential health risks. This book is a so …
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€116.96
Victor R Preedy & Ronald Ross Watson: Fruits, Vegetables, and Herbs
Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion brings together experts from around the world working on the cutting edge of research on fruit, vegetables, and herbs in health prom …
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€127.47
Ronald Ross Watson: Physical Activity and the Aging Brain
Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline …
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€97.56
Ronald Ross Watson & Sherma Zibadi: Nutritional Modulators of Pain in the Aging Population
Nutritional Modulators of Pain in the Aging Population provides an overview on the role of foods, dietary supplements, obesity, and nutrients in the prevention and amelioration of pain in various dis …
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€121.96
William D. S. Killgore & Ronald Ross Watson: Nutrition and Lifestyle in Neurological Autoimmune Diseases
Nutrition and Lifestyle in Neurological Autoimmune Diseases: Multiple Sclerosis discusses important discoveries relating to the types of, and efficacy of, nutritional and lifestyle responses to sympt …
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€121.65
Ronald Ross Watson & Sherma Zibadi: Addictive Substances and Neurological Disease
Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, …
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€98.19
Ronald Ross Watson: Nutrition and Functional Foods for Healthy Aging
Nutrition and Functional Foods for Healthy Aging aims to equip anyone studying geriatric nutrition or working with aging adults with the latest scientific reviews of critical topics. The major object …
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€141.58
Robert J Collier & Victor R Preedy: Nutrients in Dairy and Their Implications for Health and Disease
Nutrients in Dairy and Their Implications for Health and Disease addresses various dairy products and their impact on health. This comprehensive book is divided into three sections and presents a bal …
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€205.94
Victor R Preedy & Ronald Ross Watson: HIV/AIDS
HIV/AIDS: Oxidative Stress and Dietary Antioxidants provides comprehensive coverage of oxidative stress in HIV/AIDS, focusing on both the pathological process around molecular and cellular metabolism …
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€132.10
Robert J Collier & Victor R Preedy: Dairy in Human Health and Disease across the Lifespan
Dairy in Human Health and Disease across the Lifespan addresses the contribution of milk to the human diet and health throughout the life span. This comprehensive book is divided into three sections …
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€205.40
Ronald Ross Watson & Sherma Zibadi: Lifestyle in Heart Health and Disease
Lifestyle and Heart Health and Disease provides a comprehensive evaluation of lifestyle factors that modify heart function and structure. It includes coverage of a wide range of lifestyle factors, in …
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€181.70
Victor R Preedy & Ronald Ross Watson: Polyphenols: Mechanisms of Action in Human Health and Disease
Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the …
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€250.33
Victor R Preedy & Ronald Ross Watson: Polyphenols: Prevention and Treatment of Human Disease
Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, ob …
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€251.93
Ram B. Singh & Toru Takahashi: Role of Functional Food Security in Global Health
The Role of Functional Food Security in Global Health presents a collective approach to food security through the use of functional foods as a strategy to prevent under nutrition and related diseases …
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€199.44
Ronald Ross Watson: Polyphenols in Plants
Polyphenols in Plants: Isolation, Purification and Extract Preparation, 2nd edition, provides a detailed insight into polyphenols that occur naturally in plants and how they can be affected during gr …
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€146.19
Ronald Ross Watson: Nutrition in the Prevention and Treatment of Abdominal Obesity
Nutrition in the Prevention and Treatment of Abdominal Obesity, Second Edition focuses on the important role that exercise, dietary changes and foods play in promoting and reducing visceral fat. Nutr …
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€250.84
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases
Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases, Second Edition is a valuable scientific resource that focuses on the latest advances in bioactive food research and th …
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€276.01
Victor R Preedy & Ronald Ross Watson: Bioactive Food as Dietary Interventions for Diabetes
Bioactive Food as Dietary Interventions for Diabetes, Second Edition is a valuable scientific resource that explores the latest advances in bioactive food research and the potential benefits of bioac …
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€276.04
Victor R Preedy & Ronald Ross Watson: Dietary Interventions in Liver Disease
Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. I …
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€174.14
Victor R Preedy & Ronald Ross Watson: Dietary Interventions in Gastrointestinal Diseases
Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in t …
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€173.75
Victor R Preedy & Ronald Ross Watson: Flour and Breads and Their Fortification in Health and Disease Prevention
Flour and Breads and Their Fortification in Health and Disease Prevention, Second Edition, presents the healthful benefits of flours and flour products and guides the reader on how to identify opport …
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€211.41
Victor R Preedy & Ronald Ross Watson: Omega Fatty Acids in Brain and Neurological Health
Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrat …
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€204.18
Victor R Preedy & Ronald Ross Watson: Handbook of Nutrition, Diet, and the Eye
Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perh …
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€200.25
Victor R. Preedy & Ronald Ross Watson: Nutrition and Alcohol
Over the past decade, much has been learned about the damaging effects that moderate to severe alcohol use has on tissue nutrient levels and dietary intake. In addition to alcohol’s potential to dama …
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€79.79
Victor R. Preedy & Ronald Ross Watson: Reviews in Food and Nutrition Toxicity, Volume 4
Reviews in Food and Nutrition Toxicity, Volume 4 includes the most recent reviews of current issues involved in the toxicity of food and nutrients. With contributors from the fields of medicine, publ …
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€75.75
Victor Preedy & Ronald Ross Watson: Reviews in Food and Nutrition Toxicity
Foot and mouth disease, CJD, GM, and fears about modern methods of food production have put food safety in the spotlight. In addition, the food industry is increasingly reliant upon technological inn …
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€255.98
Victor Preedy & Ronald Ross Watson: Reviews in Food and Nutrition Toxicity
Foot and mouth disease, CJD, GM, and fears about modern methods of food production have put food safety in the spotlight. In addition, the food industry is increasingly reliant upon technological inn …
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€256.78
Victor R. Preedy & Ronald Ross Watson: Nutrition and Heart Disease
Heart disease is the primary cause of death and disability in Western countries. Research indicates that nutrition and diet play key roles in both preventing and causing many types of heart damage an …
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€283.10
David Sherman & Ronald Ross Watson: Ethanol and the Liver
Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alc …
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€69.33
Victor R. Preedy & Ronald Ross Watson: Reviews in Food and Nutrition Toxicity, Volume 4
Reviews in Food and Nutrition Toxicity, Volume 4 includes the most recent reviews of current issues involved in the toxicity of food and nutrients. With contributors from the fields of medicine, publ …
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€141.59
Victor R. Preedy & Ronald Ross Watson: Reviews in Food and Nutrition Toxicity, Volume 2
This second volume of Reviews in Food and Nutrition Toxicity follows on directly from the successes of the first volume published last year. This series disseminates important data pertaining to food …
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€150.68
Ronald Ross Watson: Alcohol and Coffee Use in the Aging
As we age, our physiology changes. Also, we tend to place less emphasis on proper nutrition. The more elderly we grow, the less resistant we become to major diseases such as cancer and heart disease. …
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€79.77
Ronald Ross Watson: Nutrition and AIDS
Evidence shows that nutritional supports can help maintain health in the HIV-infected patient by replacing lost nutrients, compensating for nutritional damage done by the retrovirus-induced immunodef …
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€297.15
Ronald Ross Watson: Vegetables, Fruits, and Herbs in Health Promotion
The use of dietary vegetables and medicinal herbs to improve health is a phenomenon that is taking society by storm. Herbal products are now a multi-billion dollar business. Even more important, this …
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€79.43
Ronald Ross Watson: Handbook of Nutrition in the Aged
Detailed Review of Nutritional Therapies Used to Combat Elderly Health Issues The combination of the aging baby-boomer generation and their increased longevity has been fortunately met with increased …
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€78.76
Raj (George Washington University, Washington, D.C., USA) Lakshman & Victor R. (King’s College, London, UK) Preedy: Nutrition, Diet Therapy, and the Liver
Well-illustrated throughout and with in-depth analyses, Nutrition, Diet Therapy, and the Liver provides a holistic understanding of the causative elements that precipitate liver disease and the nutri …
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€147.05
Victor R. Preedy & Barrie Tan: Tocotrienols
The first 90 years of vitamin E research has produced prolific and notable discoveries, but until the last few decades, attention has been given mostly to the biological activities and underlying mec …
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€102.94
Ronald Ross Watson: Addictive Behaviors in Women
In Addictive Behaviors in Women, leading experts from psychiatry, psychology, sociology, and social work concisely review the addictive process and the characteristic behaviors of women who are depen …
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€126.43
Fabien De Meester & Ronald Ross Watson: Handbook of Lipids in Human Function
Handbook of Lipids in Human Function: Fatty Acids presents current research relating to health issues whose impact may be modified by adopting personalized diets and lifestyle interventions of the co …
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€153.76
Victor R Preedy & Ronald Ross Watson: Neurological Modulation of Sleep
Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for ne …
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€198.60
Victor R Preedy & Ronald Ross Watson: Nuts and Seeds in Health and Disease Prevention
Nuts and Seeds in Health and Disease Prevention, Second Edition investigates the benefits of nuts and seeds in health and disease prevention using an organizational style that will provide easy-acces …
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€147.84
Victor R. Preedy & Ronald Ross Watson: Bioactive Foods and Extracts
Though there is considerable historical and anecdotal record for the use and efficacy of the cancer preventative properties of vegetables, fruits, and herbs, modern healthcare professionals require s …
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€248.57
Ronald Ross (University of Arizona, Tucson, USA) Watson: DHEA in Human Health and Aging
Reduced production of DHEA associated with the diseases that accompany aging has led to its use as a nutritional supplement for antiaging, metabolic support, and other purposes. While animal studies …
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€91.30
Victor R Preedy & Ronald Ross Watson: Mediterranean Diet
The Mediterranean Diet: An Evidence-Based Approach, Second Edition provides authoritative material on the many facets surrounding the complex interrelationships between diet, nutrition, health and we …
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€172.78
Victor R Preedy & Ronald Ross Watson: Olives and Olive Oil in Health and Disease Prevention
Olives and Olive Oil in Health and Disease Prevention, Second Edition expands the last releases content and coverage, including new sections on materials in packaging, the Mediterranean diet, metabol …
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€218.74
Ronald Ross Watson: Melatonin in the Promotion of Health
Melatonin is a powerful hormone and antioxidant with numerous effects on the metabolism and the health of humans. Available as a dietary supplement in the United States since 1993, it is one of the m …
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€92.79
Victor R. Preedy & Ronald Ross Watson: Nutrition and Heart Disease
Heart disease is the primary cause of death and disability in Western countries. Research indicates that nutrition and diet play key roles in both preventing and causing many types of heart damage an …
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€169.33
Victor R. Preedy & Ronald Ross Watson: Bioactive Foods and Extracts
Though there is considerable historical and anecdotal record for the use and efficacy of the cancer preventative properties of vegetables, fruits, and herbs, modern healthcare professionals require s …
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€250.84