This volume contains the main proceedings of the fourth international conference on ‘Cancer Prevention 2006, ‘ which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions; problems with Cox-2 inhibitors in tumor chemoprevention; primary and secondary prevention of gynecological, breast, gastrointestinal and genitourinary cancers. In addition, the future prospects of cancer chemoprevention are discussed.
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Genetic Risk Profiles and Biomarkers in Cancer Prevention.- A Favorable View: Progress in Cancer Prevention and Screening.- Genetic Risk Profiles for Cancer Susceptibility and Therapy Response.- Tumor Promotion as a Target of Cancer Prevention.- Insulin-Like Growth Factor-Related Signaling and Cancer Development.- Inflammation, Infection, and Cancer Prevention.- Cytokines Are a Therapeutic Target for the Prevention of Inflammation-Induced Cancers.- Prevention of Hepatocellular Carcinoma in Chronic Viral Hepatitis Patients with Cirrhosis by Carotenoid Mixture.- Cox-2 and Cancer Chemoprevention: Picking up the Pieces.- Prevention of Female and Male Genital Cancers.- Human Papillomavirus Vaccine: A New Chance to Prevent Cervical Cancer.- Prevention and Early Detection of Ovarian Cancer: Mission Impossible?.- Prevention of Prostate Cancer: More Questions than Data.- Prevention of Breast Cancer.- Primary Prevention of Breast Cancer by Hormone-Induced Differentiation.- The Genomic Signature of Breast Cancer Prevention.- Estrogen Deprivation for Breast Cancer Prevention.- Prevention of Colorectal Cancers.- Primary Dietary Prevention: Is the Fiber Story Over?.- Prevention and Early Detection of Colorectal Cancer — New Horizons.- Prevention of Skin and Brain Tumors.- New Perspectives on Melanoma Pathogenesis and Chemoprevention.- Vitamin D — An Emerging Issue in Skin Cancer Control. Implications for Public Health Practice Based on the Australian Experience.- Are Gliomas Preventable?.- The Future of Cancer (Chemo)Prevention.- Angiogenesis and Cancer Prevention: A Vision.- An Estimate of Cancer Mortality Rate Reductions in Europe and the US with 1, 000 IU of Oral Vitamin D Per Day.- Uncovering Novel Targets for Cancer Chemoprevention.- Conclusions and Summary.- Conference Summary.