This volume contains the main proceedings of the fourth international conference on ‘Cancer Prevention 2006, ‘ which was held during February 16–18, 2006, in St. Gallen, Switzerland. Written by international experts in the field, the book comprises a comprehensive update on the most recent developments in the upsurging fields of molecular biology and cancer genetics and their interactions with clinical epidemiology and cancer prevention at various levels: genetic/biologic predisposition and definition of high-risk groups; preclinical models and tumor prevention; prospects of surrogate endpoints and biomarkers; progress in imaging and detection of neoplastic precursor lesions; problems with Cox-2 inhibitors in tumor chemoprevention; primary and secondary prevention of gynecological, breast, gastrointestinal and genitourinary cancers. In addition, the future prospects of cancer chemoprevention are discussed.
Mục lục
Genetic Risk Profiles and Biomarkers in Cancer Prevention.- A Favorable View: Progress in Cancer Prevention and Screening.- Genetic Risk Profiles for Cancer Susceptibility and Therapy Response.- Tumor Promotion as a Target of Cancer Prevention.- Insulin-Like Growth Factor-Related Signaling and Cancer Development.- Inflammation, Infection, and Cancer Prevention.- Cytokines Are a Therapeutic Target for the Prevention of Inflammation-Induced Cancers.- Prevention of Hepatocellular Carcinoma in Chronic Viral Hepatitis Patients with Cirrhosis by Carotenoid Mixture.- Cox-2 and Cancer Chemoprevention: Picking up the Pieces.- Prevention of Female and Male Genital Cancers.- Human Papillomavirus Vaccine: A New Chance to Prevent Cervical Cancer.- Prevention and Early Detection of Ovarian Cancer: Mission Impossible?.- Prevention of Prostate Cancer: More Questions than Data.- Prevention of Breast Cancer.- Primary Prevention of Breast Cancer by Hormone-Induced Differentiation.- The Genomic Signature of Breast Cancer Prevention.- Estrogen Deprivation for Breast Cancer Prevention.- Prevention of Colorectal Cancers.- Primary Dietary Prevention: Is the Fiber Story Over?.- Prevention and Early Detection of Colorectal Cancer — New Horizons.- Prevention of Skin and Brain Tumors.- New Perspectives on Melanoma Pathogenesis and Chemoprevention.- Vitamin D — An Emerging Issue in Skin Cancer Control. Implications for Public Health Practice Based on the Australian Experience.- Are Gliomas Preventable?.- The Future of Cancer (Chemo)Prevention.- Angiogenesis and Cancer Prevention: A Vision.- An Estimate of Cancer Mortality Rate Reductions in Europe and the US with 1, 000 IU of Oral Vitamin D Per Day.- Uncovering Novel Targets for Cancer Chemoprevention.- Conclusions and Summary.- Conference Summary.
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