Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered. Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.
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Dil İngilizce ● Biçim PDF ● ISBN 9783642788871 ● Editör Adayapalam T. Natarajan & Gunter Obe ● Yayımcı Springer Berlin Heidelberg ● Yayınlanan 2012 ● İndirilebilir 3 kez ● Döviz EUR ● Kimlik 6381975 ● Kopya koruma Adobe DRM
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