Bacterial Cp G-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. Cp G-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
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Dil İngilizce ● Biçim PDF ● ISBN 9783642596728 ● Editör H. Wagner ● Yayımcı Springer Berlin Heidelberg ● Yayınlanan 2012 ● İndirilebilir 3 kez ● Döviz EUR ● Kimlik 6328376 ● Kopya koruma Adobe DRM
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