Bacterial Cp G-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. Cp G-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
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语言 英语 ● 格式 PDF ● ISBN 9783642596728 ● 编辑 H. Wagner ● 出版者 Springer Berlin Heidelberg ● 发布时间 2012 ● 下载 3 时 ● 货币 EUR ● ID 6328376 ● 复制保护 Adobe DRM
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