Globally, millions of deaths are reported annually due to cancers, bacterial, fungal, viral and parasitic diseases, diabetes and inflammatory conditions. Metal complexes have been extensively developed and tested for anticancer, antibacterial, antifungal, antiviral, antiparasitic, antidiabetic and anti-inflammatory properties. It is quite encouraging to learn that quite a lot of metal complexes with interesting therapeutic properties have been developed.
This concise book reviews the recent advances made in the development of gold complexes as therapeutics, highlighting the different ligand architectures that have been used for their development. The mechanisms of therapeutic action, the development of nanodrugs and the toxicity issues of gold complexes are all discussed in detail. Finally, the book reflects on the future research and development in gold complexes as therapeutic agents. Postgraduates and researchers in drug discovery and development interested in metal-based therapeutics and biomedical applications of gold will find this book enlightening.
Mục lục
- Introduction
- Emergence of Gold and its Complexes in Medicine
- Gold Complexes as Anticancer Agents
- Gold Complexes as Antibacterial Agents
- Gold Complexes as Antifungal Agents
- Gold Complexes as Antiviral Agents
- Gold Complexes as Antiparasitic Agents
- Gold Complexes as Anti-inflammatory Agents
- Nanoformulations of Therapeutic Gold Complexes
- Toxicity of Gold Complexes
- Future Research Outlooks
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