Globally, millions of deaths are reported annually due to cancers, bacterial, fungal, viral and parasitic diseases, diabetes and inflammatory conditions. Metal complexes have been extensively developed and tested for anticancer, antibacterial, antifungal, antiviral, antiparasitic, antidiabetic and anti-inflammatory properties. It is quite encouraging to learn that quite a lot of metal complexes with interesting therapeutic properties have been developed.
This concise book reviews the recent advances made in the development of gold complexes as therapeutics, highlighting the different ligand architectures that have been used for their development. The mechanisms of therapeutic action, the development of nanodrugs and the toxicity issues of gold complexes are all discussed in detail. Finally, the book reflects on the future research and development in gold complexes as therapeutic agents. Postgraduates and researchers in drug discovery and development interested in metal-based therapeutics and biomedical applications of gold will find this book enlightening.
Table of Content
Introduction
Emergence of Gold and its Complexes in Medicine
Gold Complexes as Anticancer Agents
Gold Complexes as Antibacterial Agents
Gold Complexes as Antifungal Agents
Gold Complexes as Antiviral Agents
Gold Complexes as Antiparasitic Agents
Gold Complexes as Anti-inflammatory Agents
Nanoformulations of Therapeutic Gold Complexes
Toxicity of Gold Complexes
Future Research Outlooks
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