Astrid Sigel & Helmut Sigel 
Interplay between Metal Ions and Nucleic Acids [PDF ebook] 

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Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.

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表中的内容

1. Characterization of Metal Ion-Nucleic Acid Interactions in Solution. – 2. Nucleic Acid-Metal Ion Interactions in the Solid State. – 3. Metal Ion-Promoted Conformational Changes of Oligonucleotides. – 4. G-Quadruplexes and Metal Ions. – 5. Metal Ion-Mediated DNA-Protein Interactions. – 6. Spectroscopic Investigations of Lanthanide Ion Binding to Nucleic Acids. – 7. Oxidative DNA Damage Mediated by Transition Metal Ions and Their Complexes. – 8. Metal Ion-Dependent DNAzymes and Their Applications as Biosensors. – 9. Enantioselective Catalysis at the DNA Scaffold. – 10. Alternative DNA Base Pairing through Metal Coordination. – 11. Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides. – 12. Metal Complex Derivatives of Peptide Nucleic Acids.

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语言 英语 ● 格式 PDF ● 网页 354 ● ISBN 9789400721722 ● 文件大小 9.3 MB ● 编辑 Astrid Sigel & Helmut Sigel ● 出版者 Springer Netherland ● 市 Dordrecht ● 国家 NL ● 发布时间 2012 ● 下载 24 个月 ● 货币 EUR ● ID 2241129 ● 复制保护 Adobe DRM
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