Though educational methods such as distance and e-learning have addressed our modern, knowledge-based society’s requirement for innovative approaches to performing educational activities, room for improvement still exists. Artificial Intelligence Applications in Distance Education seeks to examine the efforts made to bridge the gap between student and educator with computer applications. Through an in-depth discussion of applications employed to overcome the problems encountered during educational processes, this premier reference collection aims to enhance teachers’ and students’ educational experiences and improve their knowledge of the literature and the latest developments in educational technologies.