Cancer imposes daunting effects on the nervous system
Brain cancer is one of the most devastating diagnoses a
physician can deliver. Cancer of the nervous system can take many
different forms. Treatment is specific to the type of malignancy,
its location in the nervous system and, increasingly, its molecular
characteristics. The challenges manifest further when management
choices need to be made, and multidisciplinary approaches are
required. Additional complexities arise in children, where the
developing neurological system requires more sensitive
treatment.
Neuro-oncology unmasks the complexities to provide a
straightforward guide to cancers of the nervous system. Following a
general approach to diagnosis and treatment, the clinical aspects
of specific cancer types in adults and children are explained in
practical terms. A final section considers the effect of system
cancer on the nervous system and the side effects of treatment.
Clinical in approach, practical in execution,
Neuro-oncology will help you diagnose and manage your
patients more effectively.
Neurology in Practice
Series Editors
Robert A Gross , MD, Ph D, Department of Neurology,
University of Rochester Medical Center, Rochester, New York,
USA
Jonathan W Mink, MD, Ph D, Department of Neurology,
University of Rochester Medical Center, Rochester, New York,
USA
The Neurology in Practice series provides clinical ‘in
the office’ or ‘at the bedside’ guides to effective patient care
for neurologists. The tone is practical, not academic, with authors
offering guidance on what might be done and what should be avoided.
The books are informed by evidence-based practice and feature:
* Algorithms and guidelines where they are appropriate
* ‘Tips and Tricks’ boxes – hints on improving
outcomes
* ‘Caution’ warning boxes – hints on avoiding
complications
* ‘Science Revisited’ – quick reminder of the basic science
principles
* Summaries of key evidence and suggestions for further
reading
Tabella dei contenuti
List of Contributors, xxx
Foreword
Preface
Acknowledgements
Section I: Overview and General Aspects of Theory
1 Diagnosis of Brain Tumors: Clinical and Radiographic
Isabel Arrillaga-Romany, Eudocia Quant Lee and Patrick Y.
Wen
2 Epidemiology and Etiology
Melissa L. Bondy, Yanhong Liu and Michael Scheurer
3 General Aspects of Surgery
Brian Williams, Robert Louis and Mark Shaffrey
4 General Approach to Radiation Oncology
Jennifer S. Yu and Daphne Haas-Kogan
5 General Aspects of Chemotherapy including ‘Biologic
Agents’
Jethro Hu and Santosh Kesari
Section II: Adult Nervous System Tumors
6 Malignant Gliomas in Adulthood
Michael Ivan, Matthew Tate, and Jennifer Clarke
7 LGG and Oligodendrogliomas in Adulthood
Derek R Johnson and Kurt A. Jaeckle
8 Ependymomas
Kanwal P.S. Raghav and Mark Gilbert
9 Germ Cell Tumors and Other Pineal Region Tumors
Geneviève Legault and Jeffrey C. Allen
10 Sellar Tumors: Pituitary Adenomas and
Craniopharyngiomas
Robert G. Louis and Robert Dallapiazza and John Jane Jr.
11 Meningiomas
Wendy Sherman and Jeffrey Raizer
12 Intradural Spinal Cord Tumors
Ben Shofty, Akiva Korn, Zvi Lidar and Shlomi Constantini
Section III: Pediatric Brain Tumors
13 Gliomas in Childhood
Bruce H. Cohen
14 Embryonal Tumors
Roger J. Packer
15 Infantile Brain Tumors
Alyssa Reddy
Section IV: Systemic Concerns to the CNS and Treatment
Sequelea
16 Primary Central Nervous System Lymphomas
Jerome Graber and Antonio M.P. Omuro
17 Intracranial Metastases
Mary Welch and Thomas J. Kaley
18 Spinal Cord Compression
Melike Mut
19 Leptomeningeal Metastases
Sean Grimm and Marc Chamberlain
20 Immune Mediated Paraneoplastic Neurologic Disorders: An
Overview
Myrna R. Rosenfeld and Josep Dalmau
21 Neurotoxicity of Radiation Therapy and Chemotherapy
Eudocia C. Quant Lee
Circa l’autore
Edited by
Roger J. Packer, MD, Center for Neuroscience and Behavioral
Medicine, Brain Tumor Institute, Gilbert Family Neurofibramatosis
Institute, Children’s National, Washington, DC, USA
David Schiff, MD, Departments of Neurology, Neurological
Surgery, and Medicine, University of Virginia Health Science
Center, Charlottesville, VA, USA
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