Huntington’s disease (HD) is a progressive, fatal, dominant inherited neurodegenerative disorder caused by an unstable expansion of CAG repeats within the coding region of the IT15 gene that encodes for a protein called huntingtin (htt). The clinical hallmark of HD is a severe motor impairment, but cognitive and psychiatric symptoms are early clinical features in HD that often appear before the onset of motor signs. This book discusses the prevalence, pathogenesis and treatment of HD.
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Biçim PDF ● Sayfalar 200 ● ISBN 9781536108439 ● Editör Christina Hughes ● Yayımcı Nova Science Publishers ● Yayınlanan 2017 ● İndirilebilir 3 kez ● Döviz EUR ● Kimlik 7216364 ● Kopya koruma Adobe DRM
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