This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
Tabla de materias
Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.
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Idioma Inglés ● Formato PDF ● Páginas 262 ● ISBN 9789811981760 ● Tamaño de archivo 5.8 MB ● Editorial Springer Nature Singapore ● Ciudad Singapore ● País SG ● Publicado 2023 ● Descargable 24 meses ● Divisa EUR ● ID 8917009 ● Protección de copia DRM social