This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
表中的内容
Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.
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语言 英语 ● 格式 PDF ● 网页 262 ● ISBN 9789811981760 ● 文件大小 5.8 MB ● 年龄 02-99 年份 ● 出版者 Springer Nature Singapore ● 市 Singapore ● 国家 SG ● 发布时间 2023 ● 下载 24 个月 ● 货币 EUR ● ID 8917009 ● 复制保护 社会DRM