This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
Содержание
Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.
Купите эту электронную книгу и получите еще одну БЕСПЛАТНО!
язык английский ● Формат PDF ● страницы 262 ● ISBN 9789811981760 ● Размер файла 5.8 MB ● издатель Springer Nature Singapore ● город Singapore ● Страна SG ● опубликованный 2023 ● Загружаемые 24 месяцы ● валюта EUR ● Код товара 8917009 ● Защита от копирования Социальный DRM