Haitao Pan & Ying Yuan 
Bayesian Adaptive Design for Immunotherapy and Targeted Therapy [PDF ebook] 

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This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.

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Table of Content

Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.

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Language English ● Format PDF ● Pages 262 ● ISBN 9789811981760 ● File size 5.8 MB ● Publisher Springer Nature Singapore ● City Singapore ● Country SG ● Published 2023 ● Downloadable 24 months ● Currency EUR ● ID 8917009 ● Copy protection Social DRM

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