This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.
Innehållsförteckning
Introduction to Adaptive Design and Delayed Outcomes.- Basics of Bayesian Statistics.- Phase I Dose-finding Design.- Phase II Design for Interim Monitoring.- Phase I-II Dose-finding Design.- Drug Combination Trial Design.- Conclusion.
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Språk Engelska ● Formatera PDF ● Sidor 262 ● ISBN 9789811981760 ● Filstorlek 5.8 MB ● Utgivare Springer Nature Singapore ● Stad Singapore ● Land SG ● Publicerad 2023 ● Nedladdningsbara 24 månader ● Valuta EUR ● ID 8917009 ● Kopieringsskydd Social DRM