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Eugen Mengel
Morbus Niemann-Pick [PDF ebook]

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Die Sphingomyelinase-Defizienz Morbus Niemann-Pick Typ A & B und der intrazelluläre Lipid-Transportdefekt Morbus Niemann-Pick Typ C sind als zwei genetisch und molekularbiologisch unterschiedliche Entitäten zu betrachten. Die Darstellung der beiden Erkrankungen baut auf dem medizingeschichtlichen Kontext auf. Es wird ein Bogen von der Molekularbiologie über die klinische Darstellung bis hin zu den verschiedenen Therapieansätzen gespannt. Während die Sphingomyelinase-Defizienz das Therapieprinzip Enzymersatz nahelegt, müssen bei Niemann-Pick Typ C Therapieansätze erwogen werden, die die Substrate reduzieren.

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Bahasa Jerman ● Format PDF ● Halaman-halaman 79 ● ISBN 9783837461794 ● Saiz fail 1.6 MB ● Penerbit UNI-MED Verlag AG ● Bandar raya Bremen ● Negara DE ● Diterbitkan 2012 ● Edisi 1 ● Muat turun 24 bulan ● Mata wang EUR ● ID 7944934 ● Salin perlindungan Social DRM

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